A comparative study for evaluation of Micronuclei in Buccal Cells: A clinico-pathological study - Couverture souple

Grover, Sonal; Mujib B.R, Ahmed

 
9783659770043: A comparative study for evaluation of Micronuclei in Buccal Cells: A clinico-pathological study
Couverture souple
ISBN 10 : 3659770043 ISBN 13 : 9783659770043
Editeur : LAP LAMBERT Academic Publishing, 2015

Synopsis

Many oral cancers are preceded by clinically evident pre-malignant mucosal changes that give a warning of risk and present an opportunity for detection and preventive measures. The key to diagnosis is the early detection of mucosal changes that may represent disease and not variations of normal. Cytological study of oral cells is a nonaggressive technique that is well accepted by the patient, and is therefore an attractive option for the early diagnosis of potentially malignant lesions. The analysis of micronuclei (MNi) has gained increasing popularity as an in vitro genotoxicity test and a biomarker assay for human genotoxic exposure and effect. It is well established that potentially malignant lesions have got significant number of micronuclei, which can be used in high-risk population as a screening test. Many studies with epithelial cells have been published in the last thirty years. However, only little attention has been, until now, given to the effect of different staining procedures on the results of micronuclei assays.The aim of the present study was to investigate if, and to what extent, different stains have an effect on the results of micronuclei in exfoliated oral muco

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

Many oral cancers are preceded by clinically evident pre-malignant mucosal changes that give a warning of risk and present an opportunity for detection and preventive measures. The key to diagnosis is the early detection of mucosal changes that may represent disease and not variations of normal. Cytological study of oral cells is a nonaggressive technique that is well accepted by the patient, and is therefore an attractive option for the early diagnosis of potentially malignant lesions. The analysis of micronuclei (MNi) has gained increasing popularity as an in vitro genotoxicity test and a biomarker assay for human genotoxic exposure and effect. It is well established that potentially malignant lesions have got significant number of micronuclei, which can be used in high-risk population as a screening test. Many studies with epithelial cells have been published in the last thirty years. However, only little attention has been, until now, given to the effect of different staining procedures on the results of micronuclei assays.The aim of the present study was to investigate if, and to what extent, different stains have an effect on the results of micronuclei in exfoliated oral muco

Biographie de l'auteur

Dr. Sonal Grover a passionate oral and maxillofacial pathologist did his graduation from Govt. Dental College, Rohtak and masters from Bapuji Dental College & Hospital, Davangere. He has several international and national publications to his account and has been a reviewer for many journals.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2015
Langue
anglais
ISBN 10 
3659770043
ISBN 13 
9783659770043
Reliure
Broché
Nombre de pages
56
Coordonnées du fabricant
non disponible
Personne responsable
KreGa Onlinehandel GmbH
4950000000000
info@krega-onlinehandel.de

Birkenweg 31
Brakel
33034
Allemagne