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Salivary transcript expression profiles of Phlebotomus papatasi: Antigenic variation of phlebotomus papatasi salivary glands regarding some biological and environmental factors - Couverture souple

Hosseini-Vasoukolaei, Nasibeh; Akhavan, Amir Ahmad; Jeddi-Tehrani, Mahmood

 
9783659819407: Salivary transcript expression profiles of Phlebotomus papatasi: Antigenic variation of phlebotomus papatasi salivary glands regarding some biological and environmental factors
Couverture souple
ISBN 10 : 3659819409 ISBN 13 : 9783659819407
Editeur : LAP LAMBERT Academic Publishing, 2016

Synopsis

Zoonotic cutaneous leishmaniasis is a neglected tropical disease of public health importance in many rural areas of Iran. Saliva of phlebotomines consists of different molecules that are necessary for a sand fly to successfully take a blood meal. Additionally, previous exposure to sand fly saliva indirectly affects the establishment of Leishmania in vertebrate hosts. Sand fly saliva has immunomodulatory characteristics and induces a specific immunity consisting of antibody production and a cellular immune response. In this study we defined salivary gland proteins of wild population of Phlebotomus papatasi with various physiological characteristics at different seasons, and also the immune response of Rhombomys opimus reservoir host to different salivary antigens, to understand the natural interaction between vector, host and parasite in the study area. We also analyzed the effect of physiological and seasonal characteristics on the expression profile of sand fly salivary genes. We hope the findings of this study could be helpful in the designing of saliva-based vaccine to control the disease.

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À propos de l'auteur

Dr. Nasibeh Hosseini-Vasoukolaei was born in Mazandaran,Iran in 1983. She is faculty member of Department of Medical Entomology and Vector Control, Faculty of Health, Mazandaran University of Medical Sciences, Sari, Iran.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2016
Langue
anglais
ISBN 10 
3659819409
ISBN 13 
9783659819407
Reliure
Broché
Nombre de pages
120
Coordonnées du fabricant
non disponible
Personne responsable
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