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Psidium guajava (Goava) and Ribes americanum (Blackcurrant): Antioxidant and Antilipidaemic Efffects of the Leaves Extracts and its Fractions - Couverture souple

Khala, H M

 
9783659888380: Psidium guajava (Goava) and Ribes americanum (Blackcurrant): Antioxidant and Antilipidaemic Efffects of the Leaves Extracts and its Fractions
Couverture souple
ISBN 10 : 3659888389 ISBN 13 : 9783659888380
Editeur : LAP LAMBERT Academic Publishing, 2016

Synopsis

The antioxidant and antihyperlipidaemic activities of P. guajava and R. americanum leaves aqueous extract were studied using in vitro and in vivo experimental models. The free radical scavenging activity, lipid peroxide inhibitory effects in RBC ghost and liver homogenate lipids, effects on viability and cytotoxicity of oxidant challenged S. cerevisae and effects on rats fed on high fat feeds and salted water were studied. Sequential fractionation of the aqueous extract with hexane, methylene chloride, ethylacetate, methanol and subsequent antioxidant and antihyperlipidaemic activity of the fractions was carried out. Further fractionation of the methanol fraction of R. americanum aqueous leaves extract using column chromatography and bioassay of the fractions was undertaken. FTIR and GCMS analysis of the active fractions and subsequent identification of the active components of the fractions was also carried out. This study showed P. guajava and R. americanum leaves posses significant antioxidant and antihyperlipidaemic activity. The study also showed the leaves' Cyanidin has the antilipidaemic activity while cyanidin, kaemferol and quercetin contribute to the antioxidant activity

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Présentation de l'éditeur

The antioxidant and antihyperlipidaemic activities of P. guajava and R. americanum leaves aqueous extract were studied using in vitro and in vivo experimental models. The free radical scavenging activity, lipid peroxide inhibitory effects in RBC ghost and liver homogenate lipids, effects on viability and cytotoxicity of oxidant challenged S. cerevisae and effects on rats fed on high fat feeds and salted water were studied. Sequential fractionation of the aqueous extract with hexane, methylene chloride, ethylacetate, methanol and subsequent antioxidant and antihyperlipidaemic activity of the fractions was carried out. Further fractionation of the methanol fraction of R. americanum aqueous leaves extract using column chromatography and bioassay of the fractions was undertaken. FTIR and GCMS analysis of the active fractions and subsequent identification of the active components of the fractions was also carried out. This study showed P. guajava and R. americanum leaves posses significant antioxidant and antihyperlipidaemic activity. The study also showed the leaves' Cyanidin has the antilipidaemic activity while cyanidin, kaemferol and quercetin contribute to the antioxidant activity

Biographie de l'auteur

H M Khala is a Lecturer at the University of Maiduguri where he had his BSc and MSc Biochemistry (First Class Honours). Studied PhD Biochemistry at Bayero University and published research articles in reputable journals. M S Sule is a Professor of Biochemistry at Bayero University, Kano and held many academic and administrative responsibilities.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2016
Langue
anglais
ISBN 10 
3659888389
ISBN 13 
9783659888380
Reliure
Broché
Nombre de pages
240
Éditeur
Sule M S
Coordonnées du fabricant
non disponible
Personne responsable
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