Stability Indicating RP-HPLC Method For Combined Dosage Form: Of Nebivolol HCl and Indapamide - Couverture souple

Chaki, Imran ; Pujara, Naisarg

9783659908019: Stability Indicating RP-HPLC Method For Combined Dosage Form: Of Nebivolol HCl and Indapamide

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ISBN 10 : 3659908010 ISBN 13 : 9783659908019

Editeur : LAP LAMBERT Academic Publishing, 2016

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A simple, rapid, accurate, sensitive, precise, and isocratic RP- HPLC method was develop for analysis of Nebivolol Hydrochloride and Indapamide in combined tablet dosage form. The best separation was achieved by C-18 reversed phase column (250 mm x 4.6 mm, 5μm particle) with 50 mM Potassium dihydrogen phosphate, pH 3.5 adjusted with ortho phosphoric acid, acetonitrile and triethylamine in ratio (30:70:2 v/v) as mobile phase. Flow rate was set 1 ml/min and detection was carried out at 254 nm. Retention time of Nebivolol Hydrochloride and Indapamide was found to be 3.407 min. and 5.470 min. respectively. The Method has been validated for the combination with parameters like linearity, accuracy and precision and rubustness. Linear response for Nebivolol Hydrochloride and Indapamide were in the range of 50-150 μg/ml and 15-45 μg/ml respectively. The Percentage recoveries obtained for Nebivolol Hydrochloride and Indapamide were found to be 99.87 � 0.20 and 99.93 � 0.187 respectively. The study further extended to develop stability indicating method where acid, base, oxidation and thermal degradation was performed.

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�diteur: LAP LAMBERT Academic Publishing
Date d'�dition: 2016
Langue: anglais
ISBN 10: 3659908010
ISBN 13: 9783659908019
Reliure: Broch�
Nombre de pages: 136
Coordonn�es du fabricant: non disponible
Personne responsable: KreGa Onlinehandel GmbH
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Stability Indicating RP-HPLC Method For Combined Dosage Form

Imran Chaki

Edit� par LAP LAMBERT Academic Publishing Jun 2016, 2016

ISBN 10 : 3659908010 ISBN 13 : 9783659908019

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Vendeur : BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Allemagne

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Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -A simple, rapid, accurate, sensitive, precise, and isocratic RP- HPLC method was develop for analysis of Nebivolol Hydrochloride and Indapamide in combined tablet dosage form. The best separation was achieved by C-18 reversed phase column (250 mm x 4.6 mm, 5mim particle) with 50 mM Potassium dihydrogen phosphate, pH 3.5 adjusted with ortho phosphoric acid, acetonitrile and triethylamine in ratio (30:70:2 v/v) as mobile phase. Flow rate was set 1 ml/min and detection was carried out at 254 nm. Retention time of Nebivolol Hydrochloride and Indapamide was found to be 3.407 min. and 5.470 min. respectively. The Method has been validated for the combination with parameters like linearity, accuracy and precision and rubustness. Linear response for Nebivolol Hydrochloride and Indapamide were in the range of 50-150 mig/ml and 15-45 mig/ml respectively. The Percentage recoveries obtained for Nebivolol Hydrochloride and Indapamide were found to be 99.87 � 0.20 and 99.93 � 0.187 respectively. The study further extended to develop stability indicating method where acid, base, oxidation and thermal degradation was performed. 136 pp. Englisch. N� de r�f. du vendeur 9783659908019

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Stability Indicating RP-HPLC Method For Combined Dosage Form

Imran Chaki|Naisarg Pujara

Edit� par LAP LAMBERT Academic Publishing, 2016

ISBN 10 : 3659908010 ISBN 13 : 9783659908019

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Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Chaki ImranImran A. Chaki, Master of Pharmacy, Pharmaceutical Quality Assurance at Gujarat Technological University. Research Associate at Quest Care in Quality Assurance Department.A simple, rapid, accurate, sensitive, precise, . N� de r�f. du vendeur 158248820

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Stability Indicating RP-HPLC Method For Combined Dosage Form: Of Nebivolol HCl and Indapamide

Imran Chaki

Edit� par LAP LAMBERT Academic Publishing, 2016

ISBN 10 : 3659908010 ISBN 13 : 9783659908019

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Paperback. Etat : Brand New. 136 pages. 8.66x5.91x0.31 inches. In Stock. N� de r�f. du vendeur 3659908010

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Stability Indicating RP-HPLC Method For Combined Dosage Form

Imran Chaki

Edit� par LAP LAMBERT Academic Publishing Jun 2016, 2016

ISBN 10 : 3659908010 ISBN 13 : 9783659908019

Neuf Taschenbuch

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Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -A simple, rapid, accurate, sensitive, precise, and isocratic RP- HPLC method was develop for analysis of Nebivolol Hydrochloride and Indapamide in combined tablet dosage form. The best separation was achieved by C-18 reversed phase column (250 mm x 4.6 mm, 5�m particle) with 50 mM Potassium dihydrogen phosphate, pH 3.5 adjusted with ortho phosphoric acid, acetonitrile and triethylamine in ratio (30:70:2 v/v) as mobile phase. Flow rate was set 1 ml/min and detection was carried out at 254 nm. Retention time of Nebivolol Hydrochloride and Indapamide was found to be 3.407 min. and 5.470 min. respectively. The Method has been validated for the combination with parameters like linearity, accuracy and precision and rubustness. Linear response for Nebivolol Hydrochloride and Indapamide were in the range of 50-150 �g/ml and 15-45 �g/ml respectively. The Percentage recoveries obtained for Nebivolol Hydrochloride and Indapamide were found to be 99.87 � 0.20 and 99.93 � 0.187 respectively. The study further extended to develop stability indicating method where acid, base, oxidation and thermal degradation was performed.VDM Verlag, Dudweiler Landstra�e 99, 66123 Saarbr�cken 136 pp. Englisch. N� de r�f. du vendeur 9783659908019

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Stability Indicating RP-HPLC Method For Combined Dosage Form : Of Nebivolol HCl and Indapamide

Imran Chaki

Edit� par LAP LAMBERT Academic Publishing, 2016

ISBN 10 : 3659908010 ISBN 13 : 9783659908019

Neuf Taschenbuch

impression � la demande

Vendeur : AHA-BUCH GmbH, Einbeck, Allemagne

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Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - A simple, rapid, accurate, sensitive, precise, and isocratic RP- HPLC method was develop for analysis of Nebivolol Hydrochloride and Indapamide in combined tablet dosage form. The best separation was achieved by C-18 reversed phase column (250 mm x 4.6 mm, 5mim particle) with 50 mM Potassium dihydrogen phosphate, pH 3.5 adjusted with ortho phosphoric acid, acetonitrile and triethylamine in ratio (30:70:2 v/v) as mobile phase. Flow rate was set 1 ml/min and detection was carried out at 254 nm. Retention time of Nebivolol Hydrochloride and Indapamide was found to be 3.407 min. and 5.470 min. respectively. The Method has been validated for the combination with parameters like linearity, accuracy and precision and rubustness. Linear response for Nebivolol Hydrochloride and Indapamide were in the range of 50-150 mig/ml and 15-45 mig/ml respectively. The Percentage recoveries obtained for Nebivolol Hydrochloride and Indapamide were found to be 99.87 � 0.20 and 99.93 � 0.187 respectively. The study further extended to develop stability indicating method where acid, base, oxidation and thermal degradation was performed. N� de r�f. du vendeur 9783659908019

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