In Silico Design of Hemolysin Inhibitors: of Staphylococcus haemolyticus and Wet Laboratory Applications - Couverture souple

Abdulmohsin, Bakr Mohammed Ali

 
9783659909498: In Silico Design of Hemolysin Inhibitors: of Staphylococcus haemolyticus and Wet Laboratory Applications
Couverture souple
ISBN 10 : 3659909491 ISBN 13 : 9783659909498
Editeur : LAP LAMBERT Academic Publishing, 2019

Synopsis

Staphylococcus haemolyticus strains are the second of the most frequently encountered Coagulase Negative Staphylococci that have been recognized as an emerging and important human pathogen causing serious infections such as endocarditis, urinary tract infections, septicemia, peritonitis, wound, bone and joint infections. Patients with the illnesses are usually immunocompromised, with indwelling or implanted foreign bodies . In Silico drug design represents a new approach for drug discovery and industry. This approach was used in this study to find multi-target inhibitors against the hemolysin proteins of the Staphylococcus haemolyticus which is considered the main virulence factor of this bacterium. One hundred thirty two samples were collected from wounds, ear swaps, blood cultures and from urine samples of Iraqi patients for bacterial identification from 1/12/2013 to 28/4/2014 period. Forty six of samples were diagnosed as Staphylococcus haemolyticus by biochemical tests. Almost all isolates had the ability to produce hemolysin at different degrees.

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Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2019
Langue
anglais
ISBN 10 
3659909491
ISBN 13 
9783659909498
Reliure
Broché
Nombre de pages
144
Coordonnées du fabricant
non disponible
Personne responsable
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