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A practical Introduction and Application of L-glutamine-(asparagin)ase - Couverture souple

Al-Bahrani, Maha Hameed A.; Aziz, Ghazi M.; AlKazaz, Abdul Kareem A.

 
9783659909672: A practical Introduction and Application of L-glutamine-(asparagin)ase
Couverture souple
ISBN 10 : 365990967X ISBN 13 : 9783659909672
Editeur : LAP LAMBERT Academic Publishing, 2016

Synopsis

L-glutamin-(asparagin-)ase is an amidohydrolase enzyme that catalyzes the hydrolysis of L- asparagine (L-asn) and L-glutamine(L-gln) to L-aspartate (L-asp) and L-glutamate(L- glu), respectively and releases ammonia (NH3) as well.The activity of L-glutamin-(industrial purposes. As a case in point, it can be used in the production of special chemicals, like thiamine and glutamine or acts as a biosensor for monitoring the level of L-glutamine . Clinically, decreasing the level of asparagine and/or glutamine by the administration of bacterial asparaginase and/or glutaminase or by using their antagonists is considered the common therapy for patients with acute lymphocytic leukaemia. In contrast, supplementation with asparagine and glutamine promotes a more malignant and less differentiated phenotype in human colon cancer cell lines

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

L-glutamin-(asparagin-)ase is an amidohydrolase enzyme that catalyzes the hydrolysis of L- asparagine (L-asn) and L-glutamine(L-gln) to L-aspartate (L-asp) and L-glutamate(L- glu), respectively and releases ammonia (NH3) as well.The activity of L-glutamin-(industrial purposes. As a case in point, it can be used in the production of special chemicals, like thiamine and glutamine or acts as a biosensor for monitoring the level of L-glutamine . Clinically, decreasing the level of asparagine and/or glutamine by the administration of bacterial asparaginase and/or glutaminase or by using their antagonists is considered the common therapy for patients with acute lymphocytic leukaemia. In contrast, supplementation with asparagine and glutamine promotes a more malignant and less differentiated phenotype in human colon cancer cell lines

Biographie de l'auteur

Maha Hameed AlBahrani is an Instructor at Al-Nahrain University /College of Applied Biotechnology

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2016
Langue
anglais
ISBN 10 
365990967X
ISBN 13 
9783659909672
Reliure
Broché
Nombre de pages
60
Coordonnées du fabricant
non disponible
Personne responsable
non disponible