Synthesis of Few Potential Non-Steroidal Anti-Inflammatory Agents - Couverture souple

Debnath, Biplab; Sarma, Prasanta Kumar; Mandal, Sudip Kumar

 
9783659929021: Synthesis of Few Potential Non-Steroidal Anti-Inflammatory Agents
Couverture souple
ISBN 10 : 3659929026 ISBN 13 : 9783659929021
Editeur : LAP LAMBERT Academic Publishing, 2016

Synopsis

Non-steroidal anti-inflammatory drugs are one of the commonly prescribed groups of drugs worldwide and are highly effective as analgesic, antipyretic and anti-inflammatory agents. However, their use is also associated with adverse events such as gastro duodenal ulceration and gastro intestinal bleeding. There is always a great need to develop COX-2 specific inhibitors to avoid the side effects. The present report contains a brief introduction to inflammation, biosynthesis of prostaglandins with emphasis on the enzymes COX-1 and COX-2. The main focus is on the literature survey of indan derivatives and experimental work carried out in the laboratory in an attempt to develop newer and less ulcerogenic NSAIDs.

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Présentation de l'éditeur

Non-steroidal anti-inflammatory drugs are one of the commonly prescribed groups of drugs worldwide and are highly effective as analgesic, antipyretic and anti-inflammatory agents. However, their use is also associated with adverse events such as gastro duodenal ulceration and gastro intestinal bleeding. There is always a great need to develop COX-2 specific inhibitors to avoid the side effects. The present report contains a brief introduction to inflammation, biosynthesis of prostaglandins with emphasis on the enzymes COX-1 and COX-2. The main focus is on the literature survey of indan derivatives and experimental work carried out in the laboratory in an attempt to develop newer and less ulcerogenic NSAIDs.

Biographie de l'auteur

Biplab Debnath received his M.Pharm. degree in Pharmaceutical Chemistry from MAKUT, Kolkata, India (Formerly WBUT) and Ph.D from Department of pharm. Sciences and Technology, Birla Institute of Technology, Mesra,Ranchi, India. Debnath has attended several national and international conference.he has to his credit several research publicatons.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2016
Langue
anglais
ISBN 10 
3659929026
ISBN 13 
9783659929021
Reliure
Broché
Nombre de pages
64
Coordonnées du fabricant
non disponible
Personne responsable
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