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Synthesis and Antibacterial Study of New Pyrazol-5-one Derivatives - Couverture souple

Faisal, Monther; Fadhil, Rafah; Waleed, Noor

 
9783659936890: Synthesis and Antibacterial Study of New Pyrazol-5-one Derivatives
Couverture souple
ISBN 10 : 3659936898 ISBN 13 : 9783659936890
Editeur : LAP LAMBERT Academic Publishing, 2016

Synopsis

Microwave-assisted organic synthesis result in a spectacular acceleration of many chemical reactions as a consequence of three-dimensional heating of the reaction mass which could not be reproduced by classical heating methods.It has been seen that microwave procedure has the advantages of short time, good yields, convenient workup and being environmentally friendly to afford the corresponding pyrazol-5-one derivatives. A simple one pot multicomponent reaction technique was utilized for the synthesis of novel biologically active heterocyclic ring. Most of nitrogen heterocycles are of a special interest because they constitute an important class of natural and non-natural products, among these nitrogen heterocycles are the benzothiazole containing compounds. Moreover, pyrazolone and aminonicotinonitrile nucleus are important pharmacophores that exhibits widespread pharmacological properties such as: antibacterial, antifungal, anti-inflammatory, analgesic, antipyretic, antioxidant, anticancer and antitubercular activities; these widespread applications bring us to the synthesis of new analogues of 2-mercaptobenzothiazole and of their antibacterial evaluation.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

Microwave-assisted organic synthesis result in a spectacular acceleration of many chemical reactions as a consequence of three-dimensional heating of the reaction mass which could not be reproduced by classical heating methods.It has been seen that microwave procedure has the advantages of short time, good yields, convenient workup and being environmentally friendly to afford the corresponding pyrazol-5-one derivatives. A simple one pot multicomponent reaction technique was utilized for the synthesis of novel biologically active heterocyclic ring. Most of nitrogen heterocycles are of a special interest because they constitute an important class of natural and non-natural products, among these nitrogen heterocycles are the benzothiazole containing compounds. Moreover, pyrazolone and aminonicotinonitrile nucleus are important pharmacophores that exhibits widespread pharmacological properties such as: antibacterial, antifungal, anti-inflammatory, analgesic, antipyretic, antioxidant, anticancer and antitubercular activities; these widespread applications bring us to the synthesis of new analogues of 2-mercaptobenzothiazole and of their antibacterial evaluation.

Biographie de l'auteur

Monther Faisal Mahdi,PHD in Pharmaceutical Chemistry, is currently working as the Dean of College of Pharmacy - Al Mustansiriyah University. Having an extensive knowledge in the field of Pharmacy, he has written many articles and participated in many conferences as such.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2016
Langue
anglais
ISBN 10 
3659936898
ISBN 13 
9783659936890
Reliure
Broché
Nombre de pages
148
Coordonnées du fabricant
non disponible
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