Articles liés à Bacterial pathogenecity islands

Bacterial pathogenecity islands - Couverture souple

Zaky, Mahmoud; Abousamra, Nada

 
9783659938009: Bacterial pathogenecity islands
Couverture souple
ISBN 10 : 3659938009 ISBN 13 : 9783659938009
Editeur : LAP LAMBERT Academic Publishing, 2016

Synopsis

Virulence genes of pathogenic bacteria, which code for toxins, adhesins, invasins or other virulence factors, may be located on transmissible genetic elements such as transposons, plasmids or bacteriophages. In addition, such genes may be part of particular regions on the bacterial chromosome, termed ‘pathogenicity islands’ (PAIs). Pathogenicity islands are found in Gram-negative as well as in Gram-positive bacteria. They are present in the genome of pathogenic strains of a given species but absent or only rarely present in those of non-pathogenic variants of the same or related species. They comprise large DNA regions (up to 200 kb of DNA) and often carry more than one virulence gene, the G+C contents of which often differ from those of the remaining bacterial genome. In most cases, PAIs are flanked by specific DNA sequences, such as direct repeats or insertion sequence (IS) elements. In addition, PAIs of certain bacteria (e.g. uropathogenic Escherichia coli, Yersinia spp., Helico- bacfer pylori) have the tendency to delete with high frequencies or may undergo duplication and amplifications.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

Virulence genes of pathogenic bacteria, which code for toxins, adhesins, invasins or other virulence factors, may be located on transmissible genetic elements such as transposons, plasmids or bacteriophages. In addition, such genes may be part of particular regions on the bacterial chromosome, termed ‘pathogenicity islands’ (PAIs). Pathogenicity islands are found in Gram-negative as well as in Gram-positive bacteria. They are present in the genome of pathogenic strains of a given species but absent or only rarely present in those of non-pathogenic variants of the same or related species. They comprise large DNA regions (up to 200 kb of DNA) and often carry more than one virulence gene, the G+C contents of which often differ from those of the remaining bacterial genome. In most cases, PAIs are flanked by specific DNA sequences, such as direct repeats or insertion sequence (IS) elements. In addition, PAIs of certain bacteria (e.g. uropathogenic Escherichia coli, Yersinia spp., Helico- bacfer pylori) have the tendency to delete with high frequencies or may undergo duplication and amplifications.

Biographie de l'auteur

Dr.Mahmoud.M.M.Zaky born in 23-09-1967, Cairo, Egypt. B.Sc in Botany, Suez Canal University, Egypt. M.Sc in microbiology, Joint supervision Suez Canal university and Portsmouth University,U.K. Ph.D in molecular microbiology. Joint Supervision, Mansoura University, Egypt And Munich University, Germany. Microbiology.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2016
Langue
anglais
ISBN 10 
3659938009
ISBN 13 
9783659938009
Reliure
Broché
Nombre de pages
188
Coordonnées du fabricant
non disponible
Personne responsable
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