Genetics & Tissue Engineering of Heart Valve - Couverture souple

Eslami, Maryam; Khademhosseini, Ali; Javadi, Gholamreza

 
9783659942631: Genetics & Tissue Engineering of Heart Valve
Couverture souple
ISBN 10 : 3659942634 ISBN 13 : 9783659942631
Editeur : LAP LAMBERT Academic Publishing, 2016

Synopsis

The incidence and prevalence of heart valve disease is increasing worldwide and the number of heart valve replacements is expected to increase significantly in the future. By mimicking the main tissue structures and properties of human heart value, tissue engineering offers new options for the replacements. Applying an appropriate scaffold in fabricating tissue engineered heart valves (TEHVs) is of importance since it affects the secretion of the main extracellular matrix (ECM) components, collagen 1 and elastin, which are crucial for providing the mechanical, elastic and tensile strength of TEHVs. The VICs-encapsulated composite scaffold was observed to be more inductive to ECM secretion over the PGS-PCL-only and hydrogel-only scaffolds. This composite scaffold can serve as a three-dimensional structure model for heart valve tissue engineering with the capability of providing the necessary mechanical-properties such as, elasticity and tensile strength and the ability to grow, repair and be remodelled as a tissue.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

The incidence and prevalence of heart valve disease is increasing worldwide and the number of heart valve replacements is expected to increase significantly in the future. By mimicking the main tissue structures and properties of human heart value, tissue engineering offers new options for the replacements. Applying an appropriate scaffold in fabricating tissue engineered heart valves (TEHVs) is of importance since it affects the secretion of the main extracellular matrix (ECM) components, collagen 1 and elastin, which are crucial for providing the mechanical, elastic and tensile strength of TEHVs. The VICs-encapsulated composite scaffold was observed to be more inductive to ECM secretion over the PGS-PCL-only and hydrogel-only scaffolds. This composite scaffold can serve as a three-dimensional structure model for heart valve tissue engineering with the capability of providing the necessary mechanical-properties such as, elasticity and tensile strength and the ability to grow, repair and be remodelled as a tissue.

Biographie de l'auteur

Dr. Eslami graduated with M.D, PhD degrees. She has joined in Harvard Medical School as a part of her PhD dissertation in the field of Heart valve. She has received the title of "Best 2008 Women inventor" from WIPO and 6 Gold Medals and 6 Honorary Diplomas for her medical research and has published books and papers in these fields.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2016
Langue
anglais
ISBN 10 
3659942634
ISBN 13 
9783659942631
Reliure
Broché
Nombre de pages
68
Coordonnées du fabricant
non disponible
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