Development and Optimization of Thermosensitive gel of Metoprolol - Couverture souple

Parhi, Rabinarayan

 
9783659972362: Development and Optimization of Thermosensitive gel of Metoprolol
Couverture souple
ISBN 10 : 3659972363 ISBN 13 : 9783659972362
Editeur : LAP LAMBERT Academic Publishing, 2016

Synopsis

In the recent years, with the advent of transdermal formulations which delivers the drug through the skin directed to systemic circulation is considered to be a most desirable alternative to the oral drug delivery system. Transdermal route can maintain a constant, prolonged and therapeutically effective drug levels by using intact skin as a port of drug administration. However, the skin permeability of most drugs is low but can be enhanced by physical techniques or chemical method using penetration enhancers. Among the transdermal formulations, gels and patches are frequently used for the treatment various diseases. It is always challenging to formulate and then optimize appropriate formulation from a number of experimental trials. Thus, the need of the hour for pharmaceutical sector is to design drug delivery systems with a minimum number of trials in order to obtain the appropriate formulations with target goals in minimum time. Therefore, the present work is based on the combination of design and optimization of experiments (using Design Expert software), and then the incorporation of novel penetration enhancers to develop thermosensitive transdermal gel.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

In the recent years, with the advent of transdermal formulations which delivers the drug through the skin directed to systemic circulation is considered to be a most desirable alternative to the oral drug delivery system. Transdermal route can maintain a constant, prolonged and therapeutically effective drug levels by using intact skin as a port of drug administration. However, the skin permeability of most drugs is low but can be enhanced by physical techniques or chemical method using penetration enhancers. Among the transdermal formulations, gels and patches are frequently used for the treatment various diseases. It is always challenging to formulate and then optimize appropriate formulation from a number of experimental trials. Thus, the need of the hour for pharmaceutical sector is to design drug delivery systems with a minimum number of trials in order to obtain the appropriate formulations with target goals in minimum time. Therefore, the present work is based on the combination of design and optimization of experiments (using Design Expert software), and then the incorporation of novel penetration enhancers to develop thermosensitive transdermal gel.

Biographie de l'auteur

Rabinarayan Parhi, M. Pharm, (Ph. D.), is working as Asst. Professor in pharmaceutics at GITAM Institute of Pharmacy, GITAM University, Vizag. He has more than 8 years of academic experience and has 25 publications in international and national journals. He has qualified 3 times in GATE and received IDMA award for "Best Research paper"in 2010.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2016
Langue
anglais
ISBN 10 
3659972363
ISBN 13 
9783659972362
Reliure
Broché
Nombre de pages
180
Coordonnées du fabricant
non disponible
Personne responsable
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