Thymic Development and Selection of T Lymphocytes - Couverture souple

Couverture souple

ISBN 10 : 3662511967 ISBN 13 : 9783662511961

Editeur : Springer, 2016

Synopsis

The thymus is an evolutionarily ancient primary lymphoid organ common to all vertebrates in which T cell development takes place. Failing thymus function is associated with immunodeficiency and/or autoimmunity. In this volume, leading experts provide a comprehensive overview of recent advances in thymopoiesis research. The chapters cover the development of the thymic epithelial microenvironment, address the formation of a diverse and self-tolerant repertoire of T cell receptors as the basis for cellular immunity, discuss the mechanisms by which progenitor cells colonize the thymus and detail the molecular basis for T lineage decisions. The reviews illustrate the important role of the multifaceted process of thymopoiesis for adaptive immunity.

A propos du livre

Présentation de l'éditeur

Outlining cutting-edge knowledge of the T cell-manufacturing thymus, a primal organ common to all vertebrates, this book by leading researchers covers key aspects of thymopoiesis and opens promising new vistas in our understanding of autoimmune diseases.

Détails de l'édition

• Éditeur: Springer
• Date d'édition: 2016
• Langue: anglais
• ISBN 10: 3662511967
• ISBN 13: 9783662511961
• Reliure: Broché
• Nombre de pages: 140
• Éditeur: Boehm Thomas, Takahama Yousuke
• Coordonnées du fabricant: non disponible
• Personne responsable: CMN Printpool Inh. Mathis Neumann; https://www.also.com/ec/cms5/en_6000/6000/index.jsp; ; Friedrich-Karl-Str. 9; Hamburg; Allemagne