Articles liés à The role of neutrophil extracellular traps (NETs) in...
The role of neutrophil extracellular traps (NETs) in the pathogenesis and differentiation of equine asthma phenotypes - Couverture souple
Résultats de recherche pour The role of neutrophil extracellular traps (NETs) in...
Image fournie par le vendeur
The role of neutrophil extracellular traps (NETs) in the pathogenesis and differentiation of equine asthma phenotypes
Edité par
Cuvillier, Cuvillier Apr 2025, 2025
ISBN 10 : 3689527287
ISBN 13 : 9783689527280
Neuf
Taschenbuch
Vendeur : BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Allemagne
Évaluation du vendeur 5 sur 5 étoiles
Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Equine asthma (EA) is the most prevalent chronic lung disease in horses. The immunological processes are only partially understood. Neutrophils are the primary effector cell in severe EA (sEA) and essential components of the innate immune defence. One defence mechanism is the release of neutrophil extracellular traps (NETs). NETs have the ability to capture and kill pathogens; however, they can also contribute to autoimmune responses, chronic inflammation and host damage if not properly regulated. The aim of this study was to characterise the role of NETs in the pathogenesis of EA. Analysis of BALF revealed the highest numbers of NET activated cells in sEA, in addition to elevated levels of equine cathelicidin and reduced DNase activity. Isolated blood neutrophils from horses with EA showed increased NET formation in vitro, which correlated with the clinical severity and a decrease in the cellular cholesterol content. Neutrophil cholesterol further correlated with clinical parameters associated with disease severity. The presence of circulating anti-neutrophil cytoplasmic antibodies (ANCAs) suggested local and systemic NET-related alterations. The findings of this study provide novel insights into immunological alterations in EA, with potential for the development of diagnostic and therapeutic strategies targeting NET formation and associated immune dysfunction. 182 pp. Englisch. N° de réf. du vendeur 9783689527280
Acheter neuf
EUR 62,37
Expédition à EUR 23
Expédition depuis Allemagne vers Etats-Unis
Expédition depuis Allemagne vers Etats-Unis
Quantité disponible : 2 disponible(s)
Image fournie par le vendeur
The role of neutrophil extracellular traps (NETs) in the pathogenesis and differentiation of equine asthma phenotypes
impression à la demandeVendeur : AHA-BUCH GmbH, Einbeck, Allemagne
Évaluation du vendeur 5 sur 5 étoiles
Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Equine asthma (EA) is the most prevalent chronic lung disease in horses. The immunological processes are only partially understood. Neutrophils are the primary effector cell in severe EA (sEA) and essential components of the innate immune defence. One defence mechanism is the release of neutrophil extracellular traps (NETs). NETs have the ability to capture and kill pathogens; however, they can also contribute to autoimmune responses, chronic inflammation and host damage if not properly regulated. The aim of this study was to characterise the role of NETs in the pathogenesis of EA. Analysis of BALF revealed the highest numbers of NET activated cells in sEA, in addition to elevated levels of equine cathelicidin and reduced DNase activity. Isolated blood neutrophils from horses with EA showed increased NET formation in vitro, which correlated with the clinical severity and a decrease in the cellular cholesterol content. Neutrophil cholesterol further correlated with clinical parameters associated with disease severity. The presence of circulating anti-neutrophil cytoplasmic antibodies (ANCAs) suggested local and systemic NET-related alterations. The findings of this study provide novel insights into immunological alterations in EA, with potential for the development of diagnostic and therapeutic strategies targeting NET formation and associated immune dysfunction. N° de réf. du vendeur 9783689527280
Acheter neuf
EUR 62,37
Expédition à EUR 35
Expédition depuis Allemagne vers Etats-Unis
Expédition depuis Allemagne vers Etats-Unis
Quantité disponible : 1 disponible(s)
Image fournie par le vendeur
The role of neutrophil extracellular traps (NETs) in the pathogenesis and differentiation of equine asthma phenotypes
Edité par
Cuvillier, Cuvillier Apr 2025, 2025
ISBN 10 : 3689527287
ISBN 13 : 9783689527280
Neuf
Taschenbuch
Vendeur : buchversandmimpf2000, Emtmannsberg, BAYE, Allemagne
Évaluation du vendeur 5 sur 5 étoiles
Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -Equine asthma (EA) is the most prevalent chronic lung disease in horses. The immunological processes are only partially understood. Neutrophils are the primary effector cell in severe EA (sEA) and essential components of the innate immune defence. One defence mechanism is the release of neutrophil extracellular traps (NETs). NETs have the ability to capture and kill pathogens; however, they can also contribute to autoimmune responses, chronic inflammation and host damage if not properly regulated. The aim of this study was to characterise the role of NETs in the pathogenesis of EA. Analysis of BALF revealed the highest numbers of NET activated cells in sEA, in addition to elevated levels of equine cathelicidin and reduced DNase activity. Isolated blood neutrophils from horses with EA showed increased NET formation in vitro, which correlated with the clinical severity and a decrease in the cellular cholesterol content. Neutrophil cholesterol further correlated with clinical parameters associated with disease severity. The presence of circulating anti-neutrophil cytoplasmic antibodies (ANCAs) suggested local and systemic NET-related alterations. The findings of this study provide novel insights into immunological alterations in EA, with potential for the development of diagnostic and therapeutic strategies targeting NET formation and associated immune dysfunction.Cuvillier Verlag, Nonnenstieg 8, 37075 Göttingen 186 pp. Englisch. N° de réf. du vendeur 9783689527280
Acheter neuf
EUR 62,37
Expédition à EUR 60
Expédition depuis Allemagne vers Etats-Unis
Expédition depuis Allemagne vers Etats-Unis
Quantité disponible : 1 disponible(s)
Image fournie par le vendeur
The role of neutrophil extracellular traps (NETs) in the pathogenesis and differentiation of equine asthma phenotypes
impression à la demandeVendeur : preigu, Osnabrück, Allemagne
Évaluation du vendeur 5 sur 5 étoiles
Taschenbuch. Etat : Neu. The role of neutrophil extracellular traps (NETs) in the pathogenesis and differentiation of equine asthma phenotypes | Lia Kristin Meiseberg | Taschenbuch | Wissenschaftliche Reihe der Klinik für Pferde 64 | Englisch | 2025 | Cuvillier | EAN 9783689527280 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu Print on Demand. N° de réf. du vendeur 132640737
Acheter neuf
EUR 62,37
Expédition à EUR 70
Expédition depuis Allemagne vers Etats-Unis
Expédition depuis Allemagne vers Etats-Unis
Quantité disponible : 5 disponible(s)