Homocysteine in Protein Structure/Function and Human Disease: Chemical Biology of Homocysteine-containing Proteins - Couverture souple

Jakubowski, Hieronim

Couverture souple

ISBN 10 : 370911411X ISBN 13 : 9783709114117

Editeur : Springer, 2013

Synopsis

1. Introduction.- 2. Homocysteine. Chemical Synthesis.- Physicochemical Properties.- Quantification Methods.- Metabolic Pathways.- Clinical significance.- 3. Homocysteine Thiolactone.- Chemical Synthesis.- Physicochemical Properties.- Quantification Methods.- Biological Formation and Turnover.- Clinical Significance.- 4. N-Homocysteinylated Proteins.- Functional Consequences.- Albumin.- Fibrinogen.- Cytochrome c.- Other Proteins.- Quantification Methods.- Total N-homocysteinylation assays.- Site-specific N-homocysteinylation assays.- Formation in vivo.- Turnover to Nε-Homocysteinyl-lysine.- Biological Consequences and Clinical Significance.- 5. S-Homocysteinylated Proteins.- Formation in vitro.- Functional Consequences.- Annexin.- Metallothionein.- Fibrilin, Fibronectin, Tropoelastin.- Detection in vivo.- Biological consequences.- Conclusions.- References. ​

Détails de l'édition

• Éditeur: Springer
• Date d'édition: 2013
• Langue: anglais
• ISBN 10: 370911411X
• ISBN 13: 9783709114117
• Reliure: Taschenbuch
• Coordonnées du fabricant: non disponible
• Personne responsable: CMN Printpool Inh. Mathis Neumann; https://www.also.com/ec/cms5/en_6000/6000/index.jsp; ; Friedrich-Karl-Str. 9; Hamburg; Allemagne