This study presents an in-depth examination of the extracellular matrix protein tenascin. It considers the hypothesis that the counteradhesive forces are as important as adhesive forces not only in shaping the embryo during early morphogenesis, but also in maintaining adult tissue integrity, and in restructuring morphology during regeneration and disease. The broad scope of presentations on tenascin and its relationship with other counteradhesive molecules provides a basis for understanding the phenomena of counteradhesion in morphosis, regeneration and disease.
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