Synopsis
Describing the latest research and clinical advances in what has become a rapidly-evolving field, this book covers the scope of nicotinic pharmacology. Highlights include: the identification and molecular structure of nicotinic receptor subtypes; neuronal, trophic and endocrine effects of nicotine; nicotinic receptor regulation and tolerance; pharmacological actions of nicotine metabolites; the role of nicotine in tobacco smoking; and teratogenic effects of nicotine. The potential therapeutic benefits of nicotinic drugs in Parkinson's disease, Alzheimer's disease, Tourette's syndrome and ulcerative colitis are also discussed. This book should be of interest to pharmacologists, toxicologists, neuroscientists, behavioural scientists and medical doctors. It should also be a useful reference for those involved with the social problems related to tobacco consumption.
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