Articles liés à Proton Pump Inhibitors
Synopsis
Inhibition of the proton pump in the parietal cells has been established as the main therapeutic principle in the treatment of acid-related diseases, such as peptic ulcer and gastro-oesophageal reflux. The proton pump inhi- bitors are tailored for their purpose. They accumulate in the target cell, are activated by acid and bind strongly to the specific target - the proton pump. The clinical superiority of the proton pump inhibitors is due not only to their high efficacy but also to the long duration of the acid inhibition in comparison with other antisecretory drugs. At present when drug discovery mostly relies on identification and characterization of potential targets by genome research, molecular biology, combinatorial chemistry and automated screening, it seems worthwhile to present the development of the tITst proton pump inhibitor - omeprazol- starting from a chemical structure with an observed antisecretory effect but also severe toxic effects that had to be eliminated. As always, basic and applied research operate luind in hand to optimize the delicate balance be- tween efficacy and safety of a new drug. This goal often involves time and many different specialists.
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Proton Pump Inhibitors (Milestones in Drug Therapy)
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Birkhäuser, 1999
ISBN 10 : 3764358971
ISBN 13 : 9783764358976
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Hardcover. Etat : As New. A fresh as new copy in publishers glazed pictorial boards. N° de réf. du vendeur green 19-11 medical red/blak boards Ama
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Proton Pump Inhibitors; Edited by L. Olbe;
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Basel, Birkhäuser Verlag, 1999
ISBN 10 : 3764358971
ISBN 13 : 9783764358976
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Gr. 8°, Hardcover. Etat : Sehr gut. Ill., 251 S. Sprache: Englisch; sehr gutes Ex. Sprache: Englisch Gewicht in Gramm: 730. N° de réf. du vendeur 12190
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Proton Pump Inhibitors (Milestones in Drug Therapy)
Vendeur : Ria Christie Collections, Uxbridge, Royaume-Uni
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Proton Pump Inhibitors (Hardcover)
Edité par
Birkhauser Verlag AG, Basel, 1999
ISBN 10 : 3764358971
ISBN 13 : 9783764358976
Neuf
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Vendeur : Grand Eagle Retail, Bensenville, IL, Etats-Unis
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Hardcover. Etat : new. Hardcover. Inhibition of the proton pump in the parietal cells has been established as the main therapeutic principle in the treatment of acid-related diseases, such as peptic ulcer and gastro-oesophageal reflux. The proton pump inhi bitors are tailored for their purpose. They accumulate in the target cell, are activated by acid and bind strongly to the specific target - the proton pump. The clinical superiority of the proton pump inhibitors is due not only to their high efficacy but also to the long duration of the acid inhibition in comparison with other antisecretory drugs. At present when drug discovery mostly relies on identification and characterization of potential targets by genome research, molecular biology, combinatorial chemistry and automated screening, it seems worthwhile to present the development of the tITst proton pump inhibitor - omeprazol- starting from a chemical structure with an observed antisecretory effect but also severe toxic effects that had to be eliminated. As always, basic and applied research operate luind in hand to optimize the delicate balance be tween efficacy and safety of a new drug. This goal often involves time and many different specialists. This monograph contains a description of the discovery and development of a new antisecretory therapy in the treatment of acid-related diseases: omeprazole, the first proton pump inhibitors, the pharmaceutical delivery system and the clinical experience with proton pump inhibitors is reviewed. Shipping may be from multiple locations in the US or from the UK, depending on stock availability. N° de réf. du vendeur 9783764358976
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Proton Pump Inhibitors
Edité par
Springer, Basel, Birkhäuser Basel Apr 1999, 1999
ISBN 10 : 3764358971
ISBN 13 : 9783764358976
Neuf
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Vendeur : BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Allemagne
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Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Inhibition of the proton pump in the parietal cells has been established as the main therapeutic principle in the treatment of acid-related diseases, such as peptic ulcer and gastro-oesophageal reflux. The proton pump inhi bitors are tailored for their purpose. They accumulate in the target cell, are activated by acid and bind strongly to the specific target - the proton pump. The clinical superiority of the proton pump inhibitors is due not only to their high efficacy but also to the long duration of the acid inhibition in comparison with other antisecretory drugs. At present when drug discovery mostly relies on identification and characterization of potential targets by genome research, molecular biology, combinatorial chemistry and automated screening, it seems worthwhile to present the development of the tITst proton pump inhibitor - omeprazol- starting from a chemical structure with an observed antisecretory effect but also severe toxic effects that had to be eliminated. As always, basic and applied research operate luind in hand to optimize the delicate balance be tween efficacy and safety of a new drug. This goal often involves time and many different specialists. 251 pp. Englisch. N° de réf. du vendeur 9783764358976
Quantité disponible : 2 disponible(s)
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Proton Pump Inhibitors
Edité par
Birkhäuser Basel, 1999
ISBN 10 : 3764358971
ISBN 13 : 9783764358976
Neuf
Couverture rigide
Vendeur : moluna, Greven, Allemagne
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Etat : New. N° de réf. du vendeur 42529264
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Proton Pump Inhibitors (Milestones in Drug Therapy)
Vendeur : California Books, Miami, FL, Etats-Unis
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Etat : New. N° de réf. du vendeur I-9783764358976
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Proton Pump Inhibitors
Edité par
Birkhauser Verlag AG, 1999
ISBN 10 : 3764358971
ISBN 13 : 9783764358976
Neuf
Couverture rigide
Vendeur : Kennys Bookshop and Art Galleries Ltd., Galway, GY, Irlande
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Etat : New. This monograph contains a description of the discovery and development of a new antisecretory therapy in the treatment of acid-related diseases: omeprazole, the first pump inhibitor. The pharmacology of different proton pump inhibitors and the pharmaceutic delivery system are reviewed. Editor(s): Olbe, Lars. Series: Milestones in Drug Therapy. Num Pages: 261 pages, biography. BIC Classification: MJH; MMG. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly. Dimension: 244 x 170 x 20. Weight in Grams: 730. . 1999. Hardback. . . . . N° de réf. du vendeur V9783764358976
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Proton Pump Inhibitors (Milestones in Drug Therapy)
Vendeur : Books Puddle, New York, NY, Etats-Unis
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Etat : New. pp. x + 251. N° de réf. du vendeur 2614419330
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Proton Pump Inhibitors
Edité par
Birkhäuser Basel, Birkhäuser Basel Apr 1999, 1999
ISBN 10 : 3764358971
ISBN 13 : 9783764358976
Neuf
Couverture rigide
Vendeur : buchversandmimpf2000, Emtmannsberg, BAYE, Allemagne
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Buch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -Inhibition of the proton pump in the parietal cells has been established as the main therapeutic principle in the treatment of acid-related diseases, such as peptic ulcer and gastro-oesophageal reflux. The proton pump inhi bitors are tailored for their purpose. They accumulate in the target cell, are activated by acid and bind strongly to the specific target - the proton pump. The clinical superiority of the proton pump inhibitors is due not only to their high efficacy but also to the long duration of the acid inhibition in comparison with other antisecretory drugs. At present when drug discovery mostly relies on identification and characterization of potential targets by genome research, molecular biology, combinatorial chemistry and automated screening, it seems worthwhile to present the development of the tITst proton pump inhibitor - omeprazol- starting from a chemical structure with an observed antisecretory effect but also severe toxic effects that had to be eliminated. As always, basic and applied research operate luind in hand to optimize the delicate balance be tween efficacy and safety of a new drug. This goal often involves time and many different specialists. 268 pp. Englisch. N° de réf. du vendeur 9783764358976
Quantité disponible : 1 disponible(s)