Regulatory T Cells in Inflammation - Couverture rigide

Couverture rigide

ISBN 10 : 3764370882 ISBN 13 : 9783764370886

Editeur : Birkhauser Verlag AG, 2005

Synopsis

Regulatory T cells are essential components of the immune system, and several different subsets of regulatory T cells have been described. Considerable regulatory function has been attributed to the CD4+CD25+ T cell subset. These cells act by suppressing adaptive and possibly innate immune responses thereby maintaining or restoring the balance between immunity and tolerance. The suppressive effects of CD4+CD25+ regulatory T cells are cell-contact-dependent but a role for soluble factors, particularly in vivo, has been suggested as well.
Recent developments and viewpoints in the field of CD4+CD25+ regulatory T cells as well as the potential use of regulatory T cells in immunotherapy of inflammatory diseases are discussed in this volume. By linking data from experimental models with recent findings from the clinic, this book will be of interest to immunologists and other biomedical researchers as well as clinicians interested in the regulation and manipulation of the immune response during inflammatory disease.

Détails de l'édition

• Éditeur: Birkhauser Verlag AG
• Date d'édition: 2005
• Langue: anglais
• ISBN 10: 3764370882
• ISBN 13: 9783764370886
• Reliure: Relié
• Nombre de pages: 251
• Éditeur: Taams Leonie S., Akbar Arne N., Wauben Marca H.M.
• Coordonnées du fabricant: GPSR Kontakt; ProductSafety@springernature.com; ; Tiergartenstr. 17; Heidelberg; 69121; Allemagne