Synthesis and Biomedical Applications of Multifunctional Polyethylene Glycol Derivatives - Couverture souple

Sokolovskaya, Ekaterina

 
9783832535223: Synthesis and Biomedical Applications of Multifunctional Polyethylene Glycol Derivatives
Couverture souple
ISBN 10 : 3832535225 ISBN 13 : 9783832535223
Editeur : Logos Verlag Berlin GmbH, 2013

Synopsis

Rapid development of biomedicine creates a continuous demand for new polymers with tailored properties for the fabrication of various biomaterials. Poly(ethylene glycol) (PEG) is particularly suitable for this purpose due to its biocompatibility and exceptional protein resistance, however introduction of new functional groups as well as the increase of their number per polymer chain is required in order to tune PEG's properties and increase its loading capacity. A general method for the anionic ring-opening polymerization of ethylene oxide and functional epoxides has been developed and utilized for the preparation of a number of multifunctional PEGs and their copolymers with PEG. The obtained polymers were either directly or after post-polymerization modification utilized for the fabrication of biomaterials. Smart hydrogels have been prepared from a multifunctional photoresponsive PEG copolymer and multifunctional hydrazide PEG. Reactive anisotropic particles suitable for either reversible sugar conjugation or dual stimuli (oxidation and UV irradiation) triggered degradation have been fabricated via electrohydrodynamic co-jetting. These new biomaterials have great potential for applications in tissue engineering and targeted drug delivery with controlled release.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Éditeur
Logos Verlag Berlin GmbH
Date d'édition
2013
Langue
anglais
ISBN 10 
3832535225
ISBN 13 
9783832535223
Reliure
Broché
Nombre de pages
197
Coordonnées du fabricant
non disponible
Personne responsable
non disponible