Adenoviral Vector Activation of Innate Immunity - Couverture souple

Hartman, Zachary Conrad

 
9783836436533: Adenoviral Vector Activation of Innate Immunity
Couverture souple
ISBN 10 : 3836436531 ISBN 13 : 9783836436533
Editeur : VDM Verlag Dr. Mueller E.K., 2008

Présentation de l'éditeur

Revision with unchanged content. Despite widespread functional prominence and utility, modified adenoviruses have yet to prove efficacious as clinical therapeutics in the United States. Extensively characterized, modified, and employed in a multitude of clinical trials and basic research approaches over the past 20 years, adenoviral vectors have fallen short of their promise of achieving clinical efficacy in gene therapy, vaccination, and immunotherapeutic approaches. While this lack of success could be attributed to many causes, the innate immune response to adenoviral infection remains one of the most prominent obstacles to efficacious adenoviral use today. This study summarizes some recent work, using in vitro and in vivo systems, that identifies the particular innate immune responses adenoviral vectors elicit. Additionally, this work highlights some recent advances that have been made in identifying gene families and factors responsible for these responses. This book is addressed to scientists, re­searchers, and medical professionals using adenoviral vectors for therapeutic means as well as researchers using these vectors as gene transfer vehicles for basic science applications.

Biographie de l'auteur

Bachelor’s degrees in Biology and Anthropology, Northwestern University, 2001. PhD in Genetics and Genomics in the study of adenoviral vectors at Duke University, 2006. Post-doctoral Fellow in Comprehensive Cancer Center at Duke University studying adenoviral vector approaches for immunotherapy from 2006-present.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
VDM Verlag Dr. Mueller E.K.
Date d'édition
2008
Langue
anglais
ISBN 10 
3836436531
ISBN 13 
9783836436533
Reliure
Broché
Nombre de pages
184
Coordonnées du fabricant
non disponible
Personne responsable
non disponible

Autres éditions populaires du même titre

9783639452969: Adenoviral Vector Activation of Innate Immunity: Cellular and Extracellular Responses and Initiation Mechanisms

Edition présentée

ISBN 10 :  3639452968 ISBN 13 :  9783639452969
Editeur : AV Akademikerverlag, 2012
Couverture souple