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Specific components of aversive odor memory in Drosophila melanogaster: Synapsin and Bruchpilot, two presynaptic proteins underlying specific phases of olfactory aversive memory in the fruit fly - Couverture souple

Knapek, Stephan

 
9783838120614: Specific components of aversive odor memory in Drosophila melanogaster: Synapsin and Bruchpilot, two presynaptic proteins underlying specific phases of olfactory aversive memory in the fruit fly
Couverture souple
ISBN 10 : 3838120612 ISBN 13 : 9783838120614
Editeur : Südwestdeutscher Verlag für Hochschulschriften, 2011

Synopsis

Memory is dynamic: after pairing an odor with electric shocks, flies form an aversive odor memory that lasts for several hours and consists of qualitatively different components. An anesthesia-sensitive memory component (ASM) decays rapidly, whereas a consolidated anesthesia-resistant memory component (ARM) lasts significantly longer. Here the author shows that the evolutionary conserved phosphoprotein Synapsin is selectively required for the labile ASM. Synapsin is associated with a reserve pool of vesicles at the presynapse and is required to maintain vesicle release specifically under sustained high frequency nerve stimulation. In contrast, the requirement of the active zone protein Bruchpilot is most pronounced in immediate vesicle release. The author shows that Bruchpilot is required for aversive olfactory memory and localizes the requirement of Bruchpilot to the Kenyon cells of the mushroom body, the second-order olfactory interneurons in Drosophila. He demonstrates that Bruchpilot preferentially functions for the consolidated ARM. Thus, different presynaptic proteins can dissociate consolidated and labile components of olfactory memory.

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9783838120614: Specific components of aversive odor memory in Drosophila melanogaster: Synapsin and Bruchpilot, two presynaptic proteins underlying specific phases of olfactory aversive memory in the fruit fly
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Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Knapek StephanStephan Knapek studied biology at the University of Wuerzburg, Germany. He did his PhD as a member of an international research training group at the department of Neurobiology and Genetics, where he studied the mechanis. N° de réf. du vendeur 5406414

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Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Memory is dynamic: after pairing an odor with electric shocks, flies form an aversive odor memory that lasts for several hours and consists of qualitatively different components. An anesthesia-sensitive memory component (ASM) decays rapidly, whereas a consolidated anesthesia-resistant memory component (ARM) lasts significantly longer. Here the author shows that the evolutionary conserved phosphoprotein Synapsin is selectively required for the labile ASM. Synapsin is associated with a reserve pool of vesicles at the presynapse and is required to maintain vesicle release specifically under sustained high frequency nerve stimulation. In contrast, the requirement of the active zone protein Bruchpilot is most pronounced in immediate vesicle release. The author shows that Bruchpilot is required for aversive olfactory memory and localizes the requirement of Bruchpilot to the Kenyon cells of the mushroom body, the second-order olfactory interneurons in Drosophila. He demonstrates that Bruchpilot preferentially functions for the consolidated ARM. Thus, different presynaptic proteins can dissociate consolidated and labile components of olfactory memory. N° de réf. du vendeur 9783838120614

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Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Memory is dynamic: after pairing an odor with electric shocks, flies form an aversive odor memory that lasts for several hours and consists of qualitatively different components. An anesthesia-sensitive memory component (ASM) decays rapidly, whereas a consolidated anesthesia-resistant memory component (ARM) lasts significantly longer. Here the author shows that the evolutionary conserved phosphoprotein Synapsin is selectively required for the labile ASM. Synapsin is associated with a reserve pool of vesicles at the presynapse and is required to maintain vesicle release specifically under sustained high frequency nerve stimulation. In contrast, the requirement of the active zone protein Bruchpilot is most pronounced in immediate vesicle release. The author shows that Bruchpilot is required for aversive olfactory memory and localizes the requirement of Bruchpilot to the Kenyon cells of the mushroom body, the second-order olfactory interneurons in Drosophila. He demonstrates that Bruchpilot preferentially functions for the consolidated ARM. Thus, different presynaptic proteins can dissociate consolidated and labile components of olfactory memory. 88 pp. Deutsch. N° de réf. du vendeur 9783838120614

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Taschenbuch. Etat : Neu. Specific components of aversive odor memory in Drosophila melanogaster | Synapsin and Bruchpilot, two presynaptic proteins underlying specific phases of olfactory aversive memory in the fruit fly | Stephan Knapek | Taschenbuch | Paperback | 88 S. | Deutsch | 2015 | Südwestdeutscher Verlag für Hochschulschriften AG Co. KG | EAN 9783838120614 | Verantwortliche Person für die EU: Südwestdt. Verl. f. Hochschulschrift., Brivibas Gatve 197, 1039 RIGA, LETTLAND, customerservice[at]vdm-vsg[dot]de | Anbieter: preigu. N° de réf. du vendeur 106907219

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