Epigenetic Analysis of Human Embryonic Stem Cells: Basics, Computational Methods, Applications - Couverture souple
Synopsis
Human embryonic stem cells (hESCs) hold promise for future cell replacement therapy because they can be induced to differentiate into a wide variety of cell types. DNA methylation is a crucial epigenetic mechanism involved in normal cellular differentiation. The author Lukas Chavez introduces into several experimental and computational methods commonly applied for the analysis of genetic and epigenetic characteristics. Subsequently, he develops and comprehensively describes computational methods for the analysis of novel genome-wide DNA methylation data. In a case study, the computational methods are applied to DNA methylation data derived from hESCs. The author analyzes the interplay between DNA methylation, histone modifications, and transcription factor binding, and investigates the effect of differential methylation on gene expression. The results given in this book extend our knowledge of interactions between genetic and epigenetic mechanisms during early differentiation of hESCs. The book is of most interest not only for stem cell biologists but also for researchers interested in computational methods available for high-throughput studies in health and disease.
Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.
À propos de l?auteur
Lukas Chávez obtained his PhD in Computational Biology at the Max-Planck-Institute for Molecular Genetics and Freie Universität Berlin. Currently, he works as a PostDoc at the Max-Planck-Institute for Molecular Genetics where he analyzes epigenetic modifications during cancer development.
Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.
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Epigenetic Analysis of Human Embryonic Stem Cells
Edité par
Südwestdeutscher Verlag Für Hochschulschriften Aug 2011, 2011
ISBN 10 : 3838127625
ISBN 13 : 9783838127620
Neuf
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Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Human embryonic stem cells (hESCs) hold promise for future cell replacement therapy because they can be induced to differentiate into a wide variety of cell types. DNA methylation is a crucial epigenetic mechanism involved in normal cellular differentiation. The author Lukas Chavez introduces into several experimental and computational methods commonly applied for the analysis of genetic and epigenetic characteristics. Subsequently, he develops and comprehensively describes computational methods for the analysis of novel genome-wide DNA methylation data. In a case study, the computational methods are applied to DNA methylation data derived from hESCs. The author analyzes the interplay between DNA methylation, histone modifications, and transcription factor binding, and investigates the effect of differential methylation on gene expression. The results given in this book extend our knowledge of interactions between genetic and epigenetic mechanisms during early differentiation of hESCs. The book is of most interest not only for stem cell biologists but also for researchers interested in computational methods available for high-throughput studies in health and disease. 140 pp. Englisch. N° de réf. du vendeur 9783838127620
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Epigenetic Analysis of Human Embryonic Stem Cells
Edité par
Südwestdeutscher Verlag für Hochschulschriften, 2011
ISBN 10 : 3838127625
ISBN 13 : 9783838127620
Neuf
Couverture souple
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Epigenetic Analysis of Human Embryonic Stem Cells | Basics, Computational Methods, Applications
Edité par
Südwestdeutscher Verlag für Hochschulschriften, 2015
ISBN 10 : 3838127625
ISBN 13 : 9783838127620
Neuf
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Vendeur : preigu, Osnabrück, Allemagne
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Taschenbuch. Etat : Neu. Epigenetic Analysis of Human Embryonic Stem Cells | Basics, Computational Methods, Applications | Lukas Chávez | Taschenbuch | 140 S. | Englisch | 2015 | Südwestdeutscher Verlag für Hochschulschriften | EAN 9783838127620 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. N° de réf. du vendeur 106744788
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Epigenetic Analysis of Human Embryonic Stem Cells
Edité par
Südwestdeutscher Verlag Für Hochschulschriften Aug 2011, 2011
ISBN 10 : 3838127625
ISBN 13 : 9783838127620
Neuf
Taschenbuch
Vendeur : buchversandmimpf2000, Emtmannsberg, BAYE, Allemagne
Évaluation du vendeur 5 sur 5 étoiles
Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -Human embryonic stem cells (hESCs) hold promise for future cell replacement therapy because they can be induced to differentiate into a wide variety of cell types. DNA methylation is a crucial epigenetic mechanism involved in normal cellular differentiation. The author Lukas Chavez introduces into several experimental and computational methods commonly applied for the analysis of genetic and epigenetic characteristics. Subsequently, he develops and comprehensively describes computational methods for the analysis of novel genome-wide DNA methylation data. In a case study, the computational methods are applied to DNA methylation data derived from hESCs. The author analyzes the interplay between DNA methylation, histone modifications, and transcription factor binding, and investigates the effect of differential methylation on gene expression. The results given in this book extend our knowledge of interactions between genetic and epigenetic mechanisms during early differentiation of hESCs. The book is of most interest not only for stem cell biologists but also for researchers interested in computational methods available for high-throughput studies in health and disease.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 140 pp. Englisch. N° de réf. du vendeur 9783838127620
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Epigenetic Analysis of Human Embryonic Stem Cells : Basics, Computational Methods, Applications
Edité par
Südwestdeutscher Verlag Für Hochschulschriften, 2011
ISBN 10 : 3838127625
ISBN 13 : 9783838127620
Neuf
Taschenbuch
Vendeur : AHA-BUCH GmbH, Einbeck, Allemagne
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Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Human embryonic stem cells (hESCs) hold promise for future cell replacement therapy because they can be induced to differentiate into a wide variety of cell types. DNA methylation is a crucial epigenetic mechanism involved in normal cellular differentiation. The author Lukas Chavez introduces into several experimental and computational methods commonly applied for the analysis of genetic and epigenetic characteristics. Subsequently, he develops and comprehensively describes computational methods for the analysis of novel genome-wide DNA methylation data. In a case study, the computational methods are applied to DNA methylation data derived from hESCs. The author analyzes the interplay between DNA methylation, histone modifications, and transcription factor binding, and investigates the effect of differential methylation on gene expression. The results given in this book extend our knowledge of interactions between genetic and epigenetic mechanisms during early differentiation of hESCs. The book is of most interest not only for stem cell biologists but also for researchers interested in computational methods available for high-throughput studies in health and disease. N° de réf. du vendeur 9783838127620
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