Articles liés à Gene Expression: From Microarrays to Functional Genomics

Gene Expression: From Microarrays to Functional Genomics - Couverture souple

Greco, Dario

 
9783838319223: Gene Expression: From Microarrays to Functional Genomics
Couverture souple
ISBN 10 : 3838319222 ISBN 13 : 9783838319223
Editeur : LAP Lambert Academic Publishing, 2010

Synopsis

The sequencing projects opened unprecedented possibilities of investigating complex aspects of living organisms. Among the high-throughput technologies based on genomic sequences, microarrays are widely used for measuring the relative quantity of messenger RNAs. The analysis of microarrays aims at selecting genes whose expression is different in different conditions followed by grouping them in functional categories, enabling a biological interpretation of the results. Methods to analyze microarray data are explored in this book. Not all the genes present in human cells are active; the housekeeping genes are expressed ubiquitously. Other genes (the tissue-selective genes) provide specific functions and they are expressed in certain cell types or tissues. Defining the tissue-selective genes is important as these genes cause disease with phenotype in the tissues where they are expressed. In this study, gene expression data is used for creating a catalog of genes in healthy human tissues. Moreover, the analysis of promoter sequences is used to predict gene networks and highlighting modules of transcription factors playing a role in the regulation of transcription.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

The sequencing projects opened unprecedented possibilities of investigating complex aspects of living organisms. Among the high-throughput technologies based on genomic sequences, microarrays are widely used for measuring the relative quantity of messenger RNAs. The analysis of microarrays aims at selecting genes whose expression is different in different conditions followed by grouping them in functional categories, enabling a biological interpretation of the results. Methods to analyze microarray data are explored in this book. Not all the genes present in human cells are active; the housekeeping genes are expressed ubiquitously. Other genes (the tissue-selective genes) provide specific functions and they are expressed in certain cell types or tissues. Defining the tissue-selective genes is important as these genes cause disease with phenotype in the tissues where they are expressed. In this study, gene expression data is used for creating a catalog of genes in healthy human tissues. Moreover, the analysis of promoter sequences is used to predict gene networks and highlighting modules of transcription factors playing a role in the regulation of transcription.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP Lambert Academic Publishing
Date d'édition
2010
Langue
anglais
ISBN 10 
3838319222
ISBN 13 
9783838319223
Reliure
Broché
Nombre de pages
72
Coordonnées du fabricant
non disponible
Personne responsable
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