Modeling and Optimization of Protein Expression: Statistical Methods and Metabolic Flux Analysis for Optimization of Recombinant Protein Production by Fungal Platforms - Couverture souple

Gheshlaghi, Reza

9783838324395: Modeling and Optimization of Protein Expression: Statistical Methods and Metabolic Flux Analysis for Optimization of Recombinant Protein Production by Fungal Platforms

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ISBN 10 : 3838324390 ISBN 13 : 9783838324395

Editeur : LAP Lambert Academic Publishing, 2009

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Scientific methods of enhancing gene expression including genomics, applied molecular biology, metabolic engineering, and combinatorial biosynthesis have been sufficiently developed to make a major impact on recombinant protein production. However, it appears that the combination of trial-and-error experimentation and molecular biology are not sufficient to design an optimum strategy to reach the goal. This book provides a thorough coverage of theoretical and design aspects of two engineering methodologies to overcome this shortcoming. Special emphasis was placed on the effect of the fermentation medium components of A.niger on a recombinant protein production. Statistically based experimental designs in a sequential manner were introduced as powerful tools and applied for medium optimization. A detailed metabolic network comprising intracellular compartments, amino acid catabolism and experimental flux measurements of the key metabolites should be developed and used for optimization purposes. The proposed strategy should be useful to professionals in the field of biotechnology who seek to understand the response of microorganisms to environmental stimuli.

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�diteur: LAP Lambert Academic Publishing
Date d'�dition: 2009
Langue: anglais
ISBN 10: 3838324390
ISBN 13: 9783838324395
Reliure: Broch�
Nombre de pages: 180
Coordonn�es du fabricant: non disponible
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Modeling and Optimization of Protein Expression

Reza Gheshlaghi

Edit� par LAP LAMBERT Academic Publishing Sep 2010, 2010

ISBN 10 : 3838324390 ISBN 13 : 9783838324395

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Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Scientific methods of enhancing gene expression including genomics, applied molecular biology, metabolic engineering, and combinatorial biosynthesis have been sufficiently developed to make a major impact on recombinant protein production. However, it appears that the combination of trial-and-error experimentation and molecular biology are not sufficient to design an optimum strategy to reach the goal. This book provides a thorough coverage of theoretical and design aspects of two engineering methodologies to overcome this shortcoming. Special emphasis was placed on the effect of the fermentation medium components of A.niger on a recombinant protein production. Statistically based experimental designs in a sequential manner were introduced as powerful tools and applied for medium optimization. A detailed metabolic network comprising intracellular compartments, amino acid catabolism and experimental flux measurements of the key metabolites should be developed and used for optimization purposes. The proposed strategy should be useful to professionals in the field of biotechnology who seek to understand the response of microorganisms to environmental stimuli. 180 pp. Englisch. N� de r�f. du vendeur 9783838324395

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Modeling and Optimization of Protein Expression

Reza Gheshlaghi|J. Scharer|A. Elkamel: M. Moo-Young

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Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Gheshlaghi Reza Reza Gheshlaghi: Assistant Professor, Department of Chemical Engineering, Ferdowsi University of Mashhad, Iran Jeno Scharer: Professor,University of Waterloo, Canada,ON Murray Moo-Young: Professor,University . N� de r�f. du vendeur 5413089

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Modeling and Optimization of Protein Expression | Statistical Methods and Metabolic Flux Analysis for Optimization of Recombinant Protein Production by Fungal Platforms

Reza Gheshlaghi (u. a.)

Edit� par LAP LAMBERT Academic Publishing, 2010

ISBN 10 : 3838324390 ISBN 13 : 9783838324395

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Taschenbuch. Etat : Neu. Modeling and Optimization of Protein Expression | Statistical Methods and Metabolic Flux Analysis for Optimization of Recombinant Protein Production by Fungal Platforms | Reza Gheshlaghi (u. a.) | Taschenbuch | 180 S. | Englisch | 2010 | LAP LAMBERT Academic Publishing | EAN 9783838324395 | Verantwortliche Person f�r die EU: BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt, info[at]bod[dot]de | Anbieter: preigu. N� de r�f. du vendeur 101402602

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Modeling and Optimization of Protein Expression

Reza Gheshlaghi

Edit� par LAP LAMBERT Academic Publishing Sep 2010, 2010

ISBN 10 : 3838324390 ISBN 13 : 9783838324395

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Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -Scientific methods of enhancing gene expression including genomics, applied molecular biology, metabolic engineering, and combinatorial biosynthesis have been sufficiently developed to make a major impact on recombinant protein production. However, it appears that the combination of trial-and-error experimentation and molecular biology are not sufficient to design an optimum strategy to reach the goal. This book provides a thorough coverage of theoretical and design aspects of two engineering methodologies to overcome this shortcoming. Special emphasis was placed on the effect of the fermentation medium components of A.niger on a recombinant protein production. Statistically based experimental designs in a sequential manner were introduced as powerful tools and applied for medium optimization. A detailed metabolic network comprising intracellular compartments, amino acid catabolism and experimental flux measurements of the key metabolites should be developed and used for optimization purposes. The proposed strategy should be useful to professionals in the field of biotechnology who seek to understand the response of microorganisms to environmental stimuli.VDM Verlag, Dudweiler Landstra�e 99, 66123 Saarbr�cken 180 pp. Englisch. N� de r�f. du vendeur 9783838324395

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Modeling and Optimization of Protein Expression : Statistical Methods and Metabolic Flux Analysis for Optimization of Recombinant Protein Production by Fungal Platforms

Reza Gheshlaghi

Edit� par LAP LAMBERT Academic Publishing, 2009

ISBN 10 : 3838324390 ISBN 13 : 9783838324395

Neuf Taschenbuch

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Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Scientific methods of enhancing gene expression including genomics, applied molecular biology, metabolic engineering, and combinatorial biosynthesis have been sufficiently developed to make a major impact on recombinant protein production. However, it appears that the combination of trial-and-error experimentation and molecular biology are not sufficient to design an optimum strategy to reach the goal. This book provides a thorough coverage of theoretical and design aspects of two engineering methodologies to overcome this shortcoming. Special emphasis was placed on the effect of the fermentation medium components of A.niger on a recombinant protein production. Statistically based experimental designs in a sequential manner were introduced as powerful tools and applied for medium optimization. A detailed metabolic network comprising intracellular compartments, amino acid catabolism and experimental flux measurements of the key metabolites should be developed and used for optimization purposes. The proposed strategy should be useful to professionals in the field of biotechnology who seek to understand the response of microorganisms to environmental stimuli. N� de r�f. du vendeur 9783838324395

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