Mouse embryonic stem (ES) cells demonstrate two unique properties (pluripotency and self-renewal) that facilitate in vitro studies of cellular differentiation into cell types of all three embryonic germ layers. Much of the recent interest in ES cell research comes from the possibility of developing cell replacement therapies for a wide range of human disorders including neurodegenerative diseases and endocrinopathies. A variety of different cell types have been generated from ES cells, most commonly via the generation of cellular aggregates called embryonic bodies (EB). Their conversion into hormone cells of the pituitary gland has not yet been investigated. This project focused on the generation of growth hormone (GH) positive cells from mouse ES cells.In conclusion, the treatment of EB and EBM bodies with differentiation media conditioned with GH3 cell media did not significantly enhance the differentiation frequency compared with basal differentiation media. The identification of GH, PRL and TSH positive cells reveals a novel differentiation pathway of mouse ES cells and opens future research on human ES cells for cell replacement therapy for human pituitary disorders.
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Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Mouse embryonic stem (ES) cells demonstrate two unique properties (pluripotency and self-renewal) that facilitate in vitro studies of cellular differentiation into cell types of all three embryonic germ layers. Much of the recent interest in ES cell research comes from the possibility of developing cell replacement therapies for a wide range of human disorders including neurodegenerative diseases and endocrinopathies. A variety of different cell types have been generated from ES cells, most commonly via the generation of cellular aggregates called embryonic bodies (EB). Their conversion into hormone cells of the pituitary gland has not yet been investigated. This project focused on the generation of growth hormone (GH) positive cells from mouse ES cells.In conclusion, the treatment of EB and EBM bodies with differentiation media conditioned with GH3 cell media did not significantly enhance the differentiation frequency compared with basal differentiation media. The identification of GH, PRL and TSH positive cells reveals a novel differentiation pathway of mouse ES cells and opens future research on human ES cells for cell replacement therapy for human pituitary disorders. 320 pp. Englisch. N° de réf. du vendeur 9783838360034
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Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: wagner josefI graduated with first class honours in medical biotechnology from the University of Abertay Dundee, Scotland, in 2002. I successfully obtained a postgraduate scholarship from the Australian Government which enabled me to. N° de réf. du vendeur 5416360
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Taschenbuch. Etat : Neu. The in vitro differentiation of mouse embryonic stem cells | The in vitro differentiation of mouse embryonic stem cells into pituitary growth hormone positive cells | Josef Wagner | Taschenbuch | 320 S. | Englisch | 2010 | LAP LAMBERT Academic Publishing | EAN 9783838360034 | Verantwortliche Person für die EU: BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt, info[at]bod[dot]de | Anbieter: preigu. N° de réf. du vendeur 101137725
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Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -Mouse embryonic stem (ES) cells demonstrate two unique properties (pluripotency and self-renewal) that facilitate in vitro studies of cellular differentiation into cell types of all three embryonic germ layers. Much of the recent interest in ES cell research comes from the possibility of developing cell replacement therapies for a wide range of human disorders including neurodegenerative diseases and endocrinopathies. A variety of different cell types have been generated from ES cells, most commonly via the generation of cellular aggregates called embryonic bodies (EB). Their conversion into hormone cells of the pituitary gland has not yet been investigated. This project focused on the generation of growth hormone (GH) positive cells from mouse ES cells.In conclusion, the treatment of EB and EBM bodies with differentiation media conditioned with GH3 cell media did not significantly enhance the differentiation frequency compared with basal differentiation media. The identification of GH, PRL and TSH positive cells reveals a novel differentiation pathway of mouse ES cells and opens future research on human ES cells for cell replacement therapy for human pituitary disorders.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 320 pp. Englisch. N° de réf. du vendeur 9783838360034
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Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Mouse embryonic stem (ES) cells demonstrate two unique properties (pluripotency and self-renewal) that facilitate in vitro studies of cellular differentiation into cell types of all three embryonic germ layers. Much of the recent interest in ES cell research comes from the possibility of developing cell replacement therapies for a wide range of human disorders including neurodegenerative diseases and endocrinopathies. A variety of different cell types have been generated from ES cells, most commonly via the generation of cellular aggregates called embryonic bodies (EB). Their conversion into hormone cells of the pituitary gland has not yet been investigated. This project focused on the generation of growth hormone (GH) positive cells from mouse ES cells.In conclusion, the treatment of EB and EBM bodies with differentiation media conditioned with GH3 cell media did not significantly enhance the differentiation frequency compared with basal differentiation media. The identification of GH, PRL and TSH positive cells reveals a novel differentiation pathway of mouse ES cells and opens future research on human ES cells for cell replacement therapy for human pituitary disorders. N° de réf. du vendeur 9783838360034
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