Articles liés à AT1a mRNA expression in rat cardiac tissue: Benefits...

AT1a mRNA expression in rat cardiac tissue: Benefits of RT- PCR in gene expression profiling - Couverture souple

Sewnath, Alesha

 
9783838376646: AT1a mRNA expression in rat cardiac tissue: Benefits of RT- PCR in gene expression profiling
Couverture souple
ISBN 10 : 3838376641 ISBN 13 : 9783838376646
Editeur : LAP LAMBERT Academic Publishing, 2010

Synopsis

Annually 9.6 million cardiovascular related deaths occur in developing countries. AT1 receptor antagonists such as Losartan? block Ang II actions in vitro and in vivo, although the molecular mechanism remains unknown. The identification of putative AT1 receptor blockers in plants and their mode of action remain elusive. Molecular techniques such as Real-time PCR provides a reliable and accurate method for use in gene expression studies. This book looks at the vivo mechanisms of a plant compound, compared to a commercial hypertension drug Losartan?, by studying their effects on AT1 mRNA gene expression in rat cardiac tissue. Findings from this book illustrate that AT1 gene expression is related to the tissue-specific action of these drugs in salt-sensitive hypertension. Analyses and research from this book may assist in providing insight to those interested in molecular techniques specifically Real Time PCR used in medical research, to those interested in hypertension and research in this area.

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Présentation de l'éditeur

Annually 9.6 million cardiovascular related deaths occur in developing countries. AT1 receptor antagonists such as Losartan? block Ang II actions in vitro and in vivo, although the molecular mechanism remains unknown. The identification of putative AT1 receptor blockers in plants and their mode of action remain elusive. Molecular techniques such as Real-time PCR provides a reliable and accurate method for use in gene expression studies. This book looks at the vivo mechanisms of a plant compound, compared to a commercial hypertension drug Losartan?, by studying their effects on AT1 mRNA gene expression in rat cardiac tissue. Findings from this book illustrate that AT1 gene expression is related to the tissue-specific action of these drugs in salt-sensitive hypertension. Analyses and research from this book may assist in providing insight to those interested in molecular techniques specifically Real Time PCR used in medical research, to those interested in hypertension and research in this area.

Biographie de l'auteur

I am a young scientist residing in South Africa with a background in Biotechnology, Medical Science and Paediatric reaseach. Having done molecular research in areas such as colorectal cancer and cardiac diseases made me realize my passion for medical research thus, my current focus lies in Peadiatric HIV, a field that I'm passionate about.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2010
Langue
anglais
ISBN 10 
3838376641
ISBN 13 
9783838376646
Reliure
Broché
Nombre de pages
76
Coordonnées du fabricant
non disponible
Personne responsable
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