Cell Cycle Control of Mammalian Neural Stem Cells: Putting a Speed Limit on G1 - Couverture souple

Calegari, Federico; Salomoni, Paolo

 
9783838381695: Cell Cycle Control of Mammalian Neural Stem Cells: Putting a Speed Limit on G1
Couverture souple
ISBN 10 : 3838381696 ISBN 13 : 9783838381695
Editeur : LAP Lambert Academic Publishing, 2010

Synopsis

The potential to unlimitedly expand and generate differentiated cell types is a key feature of somatic stem cells. Within the nervous system, cellular and environmental determinants tightly control the expansion and differentiation of neural stem cells. Importantly, a number of studies indicate that changes in cell cycle length can influence development and physiopathology of the nervous system, and may have played a role during evolution of the mammalian brain. Specifically, it has been suggested that the length of G1 can directly influence the differentiation of neural precursors. This has prompted the proposal of a model to explain how manipulation of G1 length can be used to expand neural stem cells. If validated in non-neural systems, this model may provide the means to control the proliferation vs. differentiation of somatic stem cells, which will represent a significant advance in the field.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

À propos des auteurs

Calegari Federico is group leader of the DFG-Funded Center and Cluster of Excellence for Regenerative Therapies, Dresden, Germany. Paolo Salomoni is Brian Cross Professorial Research Associate at the UCL-Cancer Institute. He leads the newly established Samantha Dickson Brain Cancer Unit, London, UK

Calegari Federico is group leader of the DFG-Funded Center and Cluster of Excellence for Regenerative Therapies, Dresden, Germany. Paolo Salomoni is Brian Cross Professorial Research Associate at the UCL-Cancer Institute. He leads the newly established Samantha Dickson Brain Cancer Unit, London, UK

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP Lambert Academic Publishing
Date d'édition
2010
Langue
anglais
ISBN 10 
3838381696
ISBN 13 
9783838381695
Reliure
Broché
Nombre de pages
68
Coordonnées du fabricant
non disponible
Personne responsable
KreGa Onlinehandel GmbH
4950000000000
info@krega-onlinehandel.de

Birkenweg 31
Brakel
33034
Allemagne