Vancomycin and Staphylococcus aureus capsule gene: Analysis Of Capsule Gene Expression In Clinical Strains of Staphylococcus aureus Exposed To Vancomycin - Couverture souple

OTOKUNEFOR, KOME; UPTON (PhD), MAT

 
9783838383989: Vancomycin and Staphylococcus aureus capsule gene: Analysis Of Capsule Gene Expression In Clinical Strains of Staphylococcus aureus Exposed To Vancomycin
Couverture souple
ISBN 10 : 3838383982 ISBN 13 : 9783838383989
Editeur : LAP LAMBERT Academic Publishing, 2010

Synopsis

With more than 10 years following the emergence of low level vancomycin resistance in Staphylococcus aureus isolates, the molecular mechanism responsible for this resistance is not fully understood. This piece of work which explores the effect of varying concentrations of vancomycin on the capsule gene expression points at a role for the S. aureus capsule in resistance with an important link noted between increased capsule gene expression and survival at lethal vancomycin concentrations. It thereby provides the scientific community with an insight into the molecular mechanisms associated with low level vancomycin resistance and raises the effect of strain genetic background on low level vancomycin resistance and treatment failure. The study also offers an in-depth exploration of relevant literature and detailed description of methods.

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Présentation de l'éditeur

With more than 10 years following the emergence of low level vancomycin resistance in Staphylococcus aureus isolates, the molecular mechanism responsible for this resistance is not fully understood. This piece of work which explores the effect of varying concentrations of vancomycin on the capsule gene expression points at a role for the S. aureus capsule in resistance with an important link noted between increased capsule gene expression and survival at lethal vancomycin concentrations. It thereby provides the scientific community with an insight into the molecular mechanisms associated with low level vancomycin resistance and raises the effect of strain genetic background on low level vancomycin resistance and treatment failure. The study also offers an in-depth exploration of relevant literature and detailed description of methods.

Biographie de l'auteur

Kome, an Assistant Lecturer in Microbiology, University of Port Harcourt Nigeria; obtained a Masters degree in Medical and Molecular Microbiology from the University of Manchester as a Commonwealth Scholar. Still funded by the Commonwealth Scholarship Commission, she is currently carrying out PhD studies at the University of Nottingham.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2010
Langue
anglais
ISBN 10 
3838383982
ISBN 13 
9783838383989
Reliure
Broché
Nombre de pages
88
Coordonnées du fabricant
non disponible
Personne responsable
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