Quantifying Synovitis in Rheumatoid Arthritis using 3T MRI Scanning: Investigating a manual segmentation method at high-field MRI - Couverture souple

Chand, Arista

 
9783838387994: Quantifying Synovitis in Rheumatoid Arthritis using 3T MRI Scanning: Investigating a manual segmentation method at high-field MRI
Couverture souple
ISBN 10 : 3838387996 ISBN 13 : 9783838387994
Editeur : LAP LAMBERT Academic Publishing, 2010

Synopsis

Rheumatoid Arthritis (RA) is a chronic systemic inflammatory disorder that primarily affects joints, often leading to functional impairment. Magnetic Resonance Imaging (MRI) scanners allow scientists and medical professionals to investigate RA pathology with more precision than conventional radiography by detecting synovitis, which is believed to be an early event in RA. Current assessments of synovitis using MRI involve the semiquantitative RA MRI scoring (RAMRIS) method, which has shown variable reliability in previous studies. The principle objectives of this study were to investigate whether a quantitative manual segmentation method could serve as an outcome measure for the assessment of synovitis by analyzing high field 3 Tesla (3T) MRI wrist images from early and established RA patients. The results showed that manual segmentation at 3T can offer a valid and reliable measurement of synovitis. However, in terms of efficiency, this method may be best used in clinical settings as a reference to which other outcome measures are compared.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

Rheumatoid Arthritis (RA) is a chronic systemic inflammatory disorder that primarily affects joints, often leading to functional impairment. Magnetic Resonance Imaging (MRI) scanners allow scientists and medical professionals to investigate RA pathology with more precision than conventional radiography by detecting synovitis, which is believed to be an early event in RA. Current assessments of synovitis using MRI involve the semiquantitative RA MRI scoring (RAMRIS) method, which has shown variable reliability in previous studies. The principle objectives of this study were to investigate whether a quantitative manual segmentation method could serve as an outcome measure for the assessment of synovitis by analyzing high field 3 Tesla (3T) MRI wrist images from early and established RA patients. The results showed that manual segmentation at 3T can offer a valid and reliable measurement of synovitis. However, in terms of efficiency, this method may be best used in clinical settings as a reference to which other outcome measures are compared.

Biographie de l'auteur

Arista commenced her tertiary studies at the University of Auckland, New Zealand, where she completed her degree in Biomedical Science with First Class Honors in 2009. Currently she is researching the neuroprotective capabilities of antibodies to a protein implicated in ischemic stroke.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2010
Langue
anglais
ISBN 10 
3838387996
ISBN 13 
9783838387994
Reliure
Broché
Nombre de pages
84
Coordonnées du fabricant
non disponible
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