Articles liés à DNA microarray transcriptional profiling of bacteriophage...

DNA microarray transcriptional profiling of bacteriophage BFK20: Expression motifs in assignation of gene functions - Couverture souple

Majtan, Tomas

 
9783838389417: DNA microarray transcriptional profiling of bacteriophage BFK20: Expression motifs in assignation of gene functions
Couverture souple
ISBN 10 : 3838389417 ISBN 13 : 9783838389417
Editeur : LAP LAMBERT Academic Publishing, 2010

Synopsis

Since its introduction in 1995, DNA microarray technology proved itself as an irreplaceable high- throughput technique providing valuable insights into the gene expression patterns and/or the genome identification of whole living organism. Unlike the traditional comparison of expression patterns from cells exposed to two different conditions, the transcriptional profiling of viral expression during time course study of host infection represent a unique technical challenge to a conventional approach. This book describes a global gene expression profiling of bacteriophage BFK20 infecting an industrial L-lysine producer Brevibacterium flavum CCM 251 determined by using the custom DNA microarrays in a loop design. New functions were assigned and/or proposed to several gene products of so far unknown function considering their co-expression pattern by utilizing ?guilt-by- association? algorithm. The study provided further insight into phage lifecycle and can be particularly useful to professionals in Virology, Molecular Biology & Biotechnology fields considering performing a viral whole genome time-course expression analysis.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

Since its introduction in 1995, DNA microarray technology proved itself as an irreplaceable high- throughput technique providing valuable insights into the gene expression patterns and/or the genome identification of whole living organism. Unlike the traditional comparison of expression patterns from cells exposed to two different conditions, the transcriptional profiling of viral expression during time course study of host infection represent a unique technical challenge to a conventional approach. This book describes a global gene expression profiling of bacteriophage BFK20 infecting an industrial L-lysine producer Brevibacterium flavum CCM 251 determined by using the custom DNA microarrays in a loop design. New functions were assigned and/or proposed to several gene products of so far unknown function considering their co-expression pattern by utilizing ?guilt-by- association? algorithm. The study provided further insight into phage lifecycle and can be particularly useful to professionals in Virology, Molecular Biology & Biotechnology fields considering performing a viral whole genome time-course expression analysis.

Biographie de l'auteur

Tomas Majtan, PharmD PhD: Studied Pharmacy at Comenius University (Bratislava, Slovakia) and received PhD in Molecular Biology at Slovak Academy of Sciences (Bratislava, Slovakia). Postdoctoral fellow at University of Denver (Aurora, CO, USA) and Research scientist at Institute of Molecular Biology (Bratislava, Slovakia).

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2010
Langue
anglais
ISBN 10 
3838389417
ISBN 13 
9783838389417
Reliure
Broché
Nombre de pages
108
Coordonnées du fabricant
non disponible
Personne responsable
KreGa Onlinehandel GmbH
4950000000000
info@krega-onlinehandel.de

Birkenweg 31
Brakel
33034
Allemagne