Articles liés à Effect of exercise on the mRNA expression of growth...
Effect of exercise on the mRNA expression of growth factors, metabolic genes and myosin heavy chain isoforms in skeletal muscles of the rat - Couverture souple
Synopsis
Dissertation / Doktorarbeit, die am 12.07.2004 erfolgreich an einer Sporthochschule in Deutschland im Fachbereich Medizin- und Naturwissenschaften eingereicht wurde. Abstract: Skeletal muscle is a complex and heterogeneous tissue capable of remarkable ad
Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.
Résultats de recherche pour Effect of exercise on the mRNA expression of growth...
Image d'archives
Effect of exercise on the mRNA expression of growth factors, metabolic genes and myosin heavy chain isoforms in skeletal muscles of the rat
Edité par
Diplomarbeiten Agentur diplom.de, 2004
ISBN 10 : 3838682939
ISBN 13 : 9783838682938
Neuf
Couverture souple
Vendeur : Lucky's Textbooks, Dallas, TX, Etats-Unis
Évaluation du vendeur 5 sur 5 étoiles
Etat : New. N° de réf. du vendeur ABLING22Oct2817100601164
Acheter neuf
EUR 89,18
Expédition à EUR 3,45
Expédition nationale : Etats-Unis
Expédition nationale : Etats-Unis
Quantité disponible : Plus de 20 disponibles
Image fournie par le vendeur
Effect of exercise on the mRNA expression of growth factors, metabolic genes and myosin heavy chain isoforms in skeletal muscles of the rat
Edité par
Diplomarbeiten Agentur diplom.de, 2004
ISBN 10 : 3838682939
ISBN 13 : 9783838682938
Neuf
Couverture souple
Vendeur : GreatBookPrices, Columbia, MD, Etats-Unis
Évaluation du vendeur 5 sur 5 étoiles
Etat : New. N° de réf. du vendeur 20896325-n
Acheter neuf
EUR 90,40
Expédition à EUR 2,28
Expédition nationale : Etats-Unis
Expédition nationale : Etats-Unis
Quantité disponible : Plus de 20 disponibles
Image d'archives
Effect of exercise on the mRNA expression of growth factors, metabolic genes and myosin heavy chain isoforms in skeletal muscles of the rat
Edité par
Diplomarbeiten Agentur diplom.de, 2004
ISBN 10 : 3838682939
ISBN 13 : 9783838682938
Neuf
Couverture souple
Vendeur : California Books, Miami, FL, Etats-Unis
Évaluation du vendeur 4 sur 5 étoiles
Etat : New. N° de réf. du vendeur I-9783838682938
Acheter neuf
EUR 93,56
Livraison gratuite
Expédition nationale : Etats-Unis
Expédition nationale : Etats-Unis
Quantité disponible : Plus de 20 disponibles
Image fournie par le vendeur
Effect of exercise on the mRNA expression of growth factors, metabolic genes and myosin heavy chain isoforms in skeletal muscles of the rat
impression à la demandeVendeur : BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Allemagne
Évaluation du vendeur 5 sur 5 étoiles
Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Doctoral Thesis / Dissertation from the year 2004 in the subject Medicine - Human Genetics, grade: 1,0, Sport Academy Cologne (Medizin- und Naturwissenschaften, Kreislaufforschung und Sportmedizin), language: English, abstract: Inhaltsangabe:Abstract:Skeletal muscle is a complex and heterogeneous tissue capable of remarkable adaptation in response to various stimuli such as exercise training. Molecular biology approaches have made a large contribution to our current understanding of how mechanical loading can alter gene expression and muscle protein synthesis rates in skeletal muscle. The steady-state level of a given mRNA is a function of both its rate of synthesis and its rate of degradation, implying that the rate of change in response to a cellular stimulus is dependent on the dynamics of mRNA turnover. Changes in muscle mRNA steady-state levels can be taken as an index of changes in gene expression, constituting currently one of the best described and understood molecular events that underlie muscle plasticity. The discovery of new growth factors involved in the regulation of muscle development provides a better understanding of the molecular mechanisms involved in the adaptation of skeletal muscle to exercise training. Since it has been shown that changes in contractile function can be brought about by switching on one subset and repressing another subset of genes, it was hypothesized that the steady state level of multiple mRNAs (growth factors and metabolic genes) involved in regulatory functions in a muscle which is frequently recruited during exercise is different between endurance trained versus untrained rats. Recent scientific data indicate that myostatin constitutes a limiting factor in normal muscle development playing a crucial role in skeletal muscle hypertrophy. Nevertheless, there are only scarce data so far about the role of myostatin in the exercise-induced skeletal muscle adaptation. The transient changes in regulatory and structural gene expression provide the molecular basis of the adaptability of the skeletal muscle to exercise stimulus. To get an insight into the molecular mechanisms of skeletal muscle adaptation, the main objective of this study was to examine the effect of both the short- and long- term effect of exercise (five day of swimming vs. chronic wheel running) on IGF-I and MSTN (positive and negative skeletal muscle regulators respectively) mRNA contents in male Wistar rats. Potential increase of positive and/or decrease of negative regulators of muscle growth lead to enhanced muscle-progenitor proliferation providing a new perspective in the mechanism of muscle adaptability. It was hypothesized that exercise training could be accompanied by an up-regulation of IGF-I and/or down-regulation of the MSTN gene (positive and negative skeletal muscle regulators respectively). Because MSTN expression has been reported to be more prominent in fast-twitch muscle, diverse skeletal muscles with different fiber type composition and recruitment patterns during movement were analyzed (gastrocnemius, vastus lateralis and soleus). In addition, MSTN was analyzed in combination with the mRNA contents of glucose transporter 4 (GLUT4), hexokinase II (HK II), and hydroxyacyl-CoA dehydrogenase (HAD), a set of well characterized metabolic genes. On the level of structural genes, myosin heavy chain (MHC) I, IIa and IIb mRNA were analyzed in gastrocnemius and vastus lateralis muscles of trained and untrained animals.Rats were studied in two experiments by using two different protocols. Initially, the effect of 5-day endurance swim training on mRNA contents of MSTN and IGF-I (growth factors), HK II, GLUT4 and HAD (metabolic genes) and MHC isofors was analyzed in gastrocnemius, vastus lateralis and soleus muscles of male Wistar rats. In a second phase, the effect of a 12-week wheel running on the mRNA contents of the above mentioned genes was analyzed in a study. 124 pp. Englisch. N° de réf. du vendeur 9783838682938
Acheter neuf
EUR 74
Expédition à EUR 23
Expédition depuis Allemagne vers Etats-Unis
Expédition depuis Allemagne vers Etats-Unis
Quantité disponible : 2 disponible(s)
Image fournie par le vendeur
Effect of exercise on the mRNA expression of growth factors, metabolic genes and myosin heavy chain isoforms in skeletal muscles of the rat
Edité par
Diplomarbeiten Agentur diplom.de, 2004
ISBN 10 : 3838682939
ISBN 13 : 9783838682938
Ancien ou d'occasion
Couverture souple
Vendeur : GreatBookPrices, Columbia, MD, Etats-Unis
Évaluation du vendeur 5 sur 5 étoiles
Etat : As New. Unread book in perfect condition. N° de réf. du vendeur 20896325
Acheter D'occasion
EUR 94,83
Expédition à EUR 2,28
Expédition nationale : Etats-Unis
Expédition nationale : Etats-Unis
Quantité disponible : Plus de 20 disponibles
Image d'archives
Effect of exercise on the mRNA expression of growth factors, metabolic genes and myosin heavy chain isoforms in skeletal muscles of the rat
impression à la demandeVendeur : PBShop.store US, Wood Dale, IL, Etats-Unis
Évaluation du vendeur 5 sur 5 étoiles
PAP. Etat : New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000. N° de réf. du vendeur L0-9783838682938
Acheter neuf
EUR 101,27
Livraison gratuite
Expédition nationale : Etats-Unis
Expédition nationale : Etats-Unis
Quantité disponible : Plus de 20 disponibles
Image d'archives
Effect of exercise on the mRNA expression of growth factors, metabolic genes and myosin heavy chain isoforms in skeletal muscles of the rat
impression à la demandeVendeur : PBShop.store UK, Fairford, GLOS, Royaume-Uni
Évaluation du vendeur 5 sur 5 étoiles
PAP. Etat : New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000. N° de réf. du vendeur L0-9783838682938
Acheter neuf
EUR 99,68
Expédition à EUR 4,85
Expédition depuis Royaume-Uni vers Etats-Unis
Expédition depuis Royaume-Uni vers Etats-Unis
Quantité disponible : Plus de 20 disponibles
Image fournie par le vendeur
Effect of exercise on the mRNA expression of growth factors, metabolic genes and myosin heavy chain isoforms in skeletal muscles of the rat
Edité par
Diplomarbeiten Agentur diplom.de, 2004
ISBN 10 : 3838682939
ISBN 13 : 9783838682938
Neuf
Couverture souple
Vendeur : GreatBookPricesUK, Woodford Green, Royaume-Uni
Évaluation du vendeur 5 sur 5 étoiles
Etat : New. N° de réf. du vendeur 20896325-n
Acheter neuf
EUR 89,94
Expédition à EUR 17,51
Expédition depuis Royaume-Uni vers Etats-Unis
Expédition depuis Royaume-Uni vers Etats-Unis
Quantité disponible : Plus de 20 disponibles
Image d'archives
Effect of exercise on the mRNA expression of growth factors, metabolic genes and myosin heavy chain isoforms in skeletal muscles of the rat
Edité par
Diplomarbeiten Agentur diplom.de, 2004
ISBN 10 : 3838682939
ISBN 13 : 9783838682938
Neuf
Couverture souple
Vendeur : Ria Christie Collections, Uxbridge, Royaume-Uni
Évaluation du vendeur 5 sur 5 étoiles
Etat : New. In. N° de réf. du vendeur ria9783838682938_new
Acheter neuf
EUR 96,45
Expédition à EUR 13,98
Expédition depuis Royaume-Uni vers Etats-Unis
Expédition depuis Royaume-Uni vers Etats-Unis
Quantité disponible : Plus de 20 disponibles
Image d'archives
Effect of exercise on the mRNA expression of growth factors, metabolic genes and myosin heavy chain isoforms in skeletal muscles of the rat
impression à la demandeVendeur : Majestic Books, Hounslow, Royaume-Uni
Évaluation du vendeur 4 sur 5 étoiles
Etat : New. Print on Demand pp. 126 424:B&W 5.83 x 8.27 in or 210 x 148 mm (A5) Perfect Bound on Creme w/Matte Lam. N° de réf. du vendeur 132846880
Acheter neuf
EUR 108,80
Expédition à EUR 7,59
Expédition depuis Royaume-Uni vers Etats-Unis
Expédition depuis Royaume-Uni vers Etats-Unis
Quantité disponible : 4 disponible(s)