Articles liés à Low Molecular Weight Poly Vinyl Alcohol Microparticles:...

Low Molecular Weight Poly Vinyl Alcohol Microparticles: Synthesis and Application: Adsorption Based Inhalable Microparticle - Couverture souple

Alas'ad, Manar

 
9783843350723: Low Molecular Weight Poly Vinyl Alcohol Microparticles: Synthesis and Application: Adsorption Based Inhalable Microparticle
Couverture souple
ISBN 10 : 3843350728 ISBN 13 : 9783843350723
Editeur : LAP LAMBERT Academic Publishing, 2012

Synopsis

Low molecular weight (Mw) polyvinyl alcohol(PVA) grades are highly functional synthetic polymer that have been widely used in many of the drug dosage forms, owing to the excellent biological compatibility of these polymers. Using partially hydrolysed grades of low Mw PVA in fabricating pulmonary drug delivery systems is becoming an attractive approach to modify the physicochemical properties of inhalable drug microparticles. The aim of this study was to synthesis partially hydrolysed low Mw PVA grades with amphiphilc properties and to assess their ability to adsorb onto the surface of micronized drug particles in order to control the drug release pattern of hydrophilic medicinal molecule. The physicochemical properties and the biocompatibility of the partially hydrolysed low molecular weight permit PVA to have the potential as carrier for sustained release pulmonary drug delivery.

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Présentation de l'éditeur

Low molecular weight (Mw) polyvinyl alcohol(PVA) grades are highly functional synthetic polymer that have been widely used in many of the drug dosage forms, owing to the excellent biological compatibility of these polymers. Using partially hydrolysed grades of low Mw PVA in fabricating pulmonary drug delivery systems is becoming an attractive approach to modify the physicochemical properties of inhalable drug microparticles. The aim of this study was to synthesis partially hydrolysed low Mw PVA grades with amphiphilc properties and to assess their ability to adsorb onto the surface of micronized drug particles in order to control the drug release pattern of hydrophilic medicinal molecule. The physicochemical properties and the biocompatibility of the partially hydrolysed low molecular weight permit PVA to have the potential as carrier for sustained release pulmonary drug delivery.

Biographie de l'auteur

Manar A. ALas'ad, MSC Pharmaceutical Technology: Studied Master of Pharmaceutical Science at King's College London. Sterile Product Development - Project Manager at Tabuk Pharmaceutical Manufacturing Co.,

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2012
Langue
anglais
ISBN 10 
3843350728
ISBN 13 
9783843350723
Reliure
Broché
Nombre de pages
96
Coordonnées du fabricant
non disponible
Personne responsable
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