Application of Self-assembled Monolayers to Cholesterol Biosensor: Preparation, Characterization and Application of Some Monolayers to Cholesterol Biosensor - Couverture souple

Arya, Sunil Kumar; Datta, Monika; D. Malhotra, Bansi

 
9783843352826: Application of Self-assembled Monolayers to Cholesterol Biosensor: Preparation, Characterization and Application of Some Monolayers to Cholesterol Biosensor
Couverture souple
ISBN 10 : 3843352828 ISBN 13 : 9783843352826
Editeur : LAP LAMBERT Academic Publishing, 2010

Synopsis

A biosensor is an integrated bioanalytical device that employs biological elements, as analyte sensor, coupled to a transducer for signal detection. Biosensor provides sensitive and selective determination of various compounds of analytical relevance. Recently, use of self-assembled monolayer (SAM) is gaining attention as biosensor matrix. SAM provides a simple route to functionalize electrode surfaces for biosensor fabrication. The alarming rise in the rates of heart diseases due to abnormal levels of cholesterol in blood has stimulated public concern about the estimation of cholesterol level in desired sample. The present book highlights the preparation, characterization and application of some SAMs for immobilization of cholesterol oxidase, cholesterol esterase & horseradish peroxidase for development of cholesterol biosensor. The fabricated bioelectrodes were tested for various parameters like pH, temperature, interferents etc. and have been utilized for free and total cholesterol estimation in solution & serum samples. The results indicate that the SAMs are likely to provide useful matrices for the fabrication of commercial cholesterol sensing bioelectrodes.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

A biosensor is an integrated bioanalytical device that employs biological elements, as analyte sensor, coupled to a transducer for signal detection. Biosensor provides sensitive and selective determination of various compounds of analytical relevance. Recently, use of self-assembled monolayer (SAM) is gaining attention as biosensor matrix. SAM provides a simple route to functionalize electrode surfaces for biosensor fabrication. The alarming rise in the rates of heart diseases due to abnormal levels of cholesterol in blood has stimulated public concern about the estimation of cholesterol level in desired sample. The present book highlights the preparation, characterization and application of some SAMs for immobilization of cholesterol oxidase, cholesterol esterase & horseradish peroxidase for development of cholesterol biosensor. The fabricated bioelectrodes were tested for various parameters like pH, temperature, interferents etc. and have been utilized for free and total cholesterol estimation in solution & serum samples. The results indicate that the SAMs are likely to provide useful matrices for the fabrication of commercial cholesterol sensing bioelectrodes.

Biographie de l'auteur

Dr Sunil Kumar Arya has received BSc (Chemistry), MSc (Organic Chemistry) and PhD (Chemistry-Biosensor) from University of Delhi and has published about 28 papers in international journals. At present, he is working as a PostDoc on MEMS based electrochem. biosensor for biomarkers (Cortisol, PSA) detection at University of South Florida, Tampa, USA.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2010
Langue
anglais
ISBN 10 
3843352828
ISBN 13 
9783843352826
Reliure
Broché
Nombre de pages
176
Coordonnées du fabricant
non disponible
Personne responsable
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