Articles liés à Modulation of protein-protein interactions: The role...

Modulation of protein-protein interactions: The role of short peptides in modulating protein-protein interactions in-vivo - Couverture souple

Dar, Altaf

 
9783843361781: Modulation of protein-protein interactions: The role of short peptides in modulating protein-protein interactions in-vivo
Couverture souple
ISBN 10 : 3843361789 ISBN 13 : 9783843361781
Editeur : LAP LAMBERT Academic Publishing, 2010

Synopsis

Interaction of proteins is central to various cellular processes like cell growth, proliferation, differentiation and programmed cell death. To study the specific role of a single protein-protein interaction of a multifunctional protein or protein complex, it is necessary to interrupt each single interaction individually to elucidate their respective role and influence they exert. In this study two approaches were employed to modulate protein interactions. First one was to target a known protein-protein interaction by expressing specific peptides in vivo. The second one was based on the LXXLL motif to disrupt interactions between transcription factors and coactivators.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

Interaction of proteins is central to various cellular processes like cell growth, proliferation, differentiation and programmed cell death. To study the specific role of a single protein-protein interaction of a multifunctional protein or protein complex, it is necessary to interrupt each single interaction individually to elucidate their respective role and influence they exert. In this study two approaches were employed to modulate protein interactions. First one was to target a known protein-protein interaction by expressing specific peptides in vivo. The second one was based on the LXXLL motif to disrupt interactions between transcription factors and coactivators.

Biographie de l'auteur

Altaf A Dar is currently working on identifying biomarkers involved in melanoma progression and metastasis at CPMC, San Francisco, CA. Previously Dr. Dar worked on gastric cancer at Vanderbilt University, Nashville, TN. Dr. Dar earned his PhD from Friedrich Schiller University, Jena Germany, where he worked on protein-protein interactions.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2010
Langue
anglais
ISBN 10 
3843361789
ISBN 13 
9783843361781
Reliure
Broché
Nombre de pages
96
Coordonnées du fabricant
non disponible
Personne responsable
KreGa Onlinehandel GmbH
4950000000000
info@krega-onlinehandel.de

Birkenweg 31
Brakel
33034
Allemagne