Signal Transducing Molecules and Colorectal Cancer - Kashmir Scenario - Couverture souple

Sameer, Aga Syed

 
9783843366564: Signal Transducing Molecules and Colorectal Cancer - Kashmir Scenario
Couverture souple
ISBN 10 : 384336656X ISBN 13 : 9783843366564
Editeur : LAP LAMBERT Academic Publishing, 2010

Synopsis

The underlying theme of this doctoral thesis was ? To evaluate the role of genetic aberrations in different signal transducing molecules of important signal transduction pathways that are involved in the development and progression of CRC in Kashmiri population. ? To assess the possible association between the genetic aberrations of the signal transducing molecules and various life style factors that are likely to lead to the development and progression of colorectal cancer. ? To observe the significance of multistep model of CRC carcinogenesis in explaining the CRC carcinogenesis in our Kashmiri population. After assessing the various signal transducing molecules for genetic aberrations we found that the multi-step model of CRC carcinogenesis holds well in explaining the CRC tumorigenesis in our Kashmiri population but with a slight difference in manner and frequency of genetic aberrations of key tumor suppressor genes and oncogenes.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

The underlying theme of this doctoral thesis was ? To evaluate the role of genetic aberrations in different signal transducing molecules of important signal transduction pathways that are involved in the development and progression of CRC in Kashmiri population. ? To assess the possible association between the genetic aberrations of the signal transducing molecules and various life style factors that are likely to lead to the development and progression of colorectal cancer. ? To observe the significance of multistep model of CRC carcinogenesis in explaining the CRC carcinogenesis in our Kashmiri population. After assessing the various signal transducing molecules for genetic aberrations we found that the multi-step model of CRC carcinogenesis holds well in explaining the CRC tumorigenesis in our Kashmiri population but with a slight difference in manner and frequency of genetic aberrations of key tumor suppressor genes and oncogenes.

Biographie de l'auteur

The author is presently working as a Senior Research Scholar in Department of Immunology & Molecular Medicine in SKIMS, Kashmir in pursuance of his doctoral degree on molecular pathogenesis of CRC in Kashmir Valley. He has completed his Master?s Degree in Biochemistry from Kashmir University. He has also qualified the prestigious CSIR-JRF.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2010
Langue
anglais
ISBN 10 
384336656X
ISBN 13 
9783843366564
Reliure
Broché
Nombre de pages
232
Coordonnées du fabricant
non disponible
Personne responsable
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