SUSTAINED RELEASE TABLET OF CARDIOVASCULAR DRUG BY MELT GRANULATION: An advanced granulation technique - Couverture souple

Bhagwat, Durgacharan; Kawtikwar, Pravin; Sakarkar, Dinesh

 
9783843387316: SUSTAINED RELEASE TABLET OF CARDIOVASCULAR DRUG BY MELT GRANULATION: An advanced granulation technique
Couverture souple
ISBN 10 : 3843387311 ISBN 13 : 9783843387316
Editeur : LAP LAMBERT Academic Publishing, 2010

Synopsis

Oral administration has been most versatile convenient and commonly employed route of drug delivery. Sustained release drug delivery system have started gaining popularity and acceptance as new drug delivery system due to better control over release for extended time. Conventionally there are two types of granulation methods i.e. wet and dry granulation. But these methods have number of disadvantages such as number of steps, equipments, labors, wastage of materials hence costly. Today's Pharmaceutical industry require minimum step, simple, continuous and efficient method. Melt granulation offers several advantages compared to conventional granulation since the liquid addition and subsequent drying step are omitted. Thus process is less consuming in terms of time and energy compared to other methods. Hence in this book an attempt has been made to develop sustained release tablet of Verapamil HCl using some lipophilic binders by melt granulation technique. Also effect of different process parameters such as concentration and type of lipophilic binders, methods of preparation, stirring time and different release enhancers on drug release was studied.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

Oral administration has been most versatile convenient and commonly employed route of drug delivery. Sustained release drug delivery system have started gaining popularity and acceptance as new drug delivery system due to better control over release for extended time. Conventionally there are two types of granulation methods i.e. wet and dry granulation. But these methods have number of disadvantages such as number of steps, equipments, labors, wastage of materials hence costly. Today's Pharmaceutical industry require minimum step, simple, continuous and efficient method. Melt granulation offers several advantages compared to conventional granulation since the liquid addition and subsequent drying step are omitted. Thus process is less consuming in terms of time and energy compared to other methods. Hence in this book an attempt has been made to develop sustained release tablet of Verapamil HCl using some lipophilic binders by melt granulation technique. Also effect of different process parameters such as concentration and type of lipophilic binders, methods of preparation, stirring time and different release enhancers on drug release was studied.

Biographie de l'auteur

Durgacharan Arun Bhagwat M. Pharm.(Industrial Pharmacy): PG at SGB Amravati University. Asst. Professor at Dept. of Pharmaceutics, Rajarambapu College of Pharmacy, Kasegaon. 2.6 yrs of teaching experience.Published 12 research papers in reputed National and International journals. Research interest in Formulation and Development of NDDS.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2010
Langue
anglais
ISBN 10 
3843387311
ISBN 13 
9783843387316
Reliure
Broché
Nombre de pages
88
Coordonnées du fabricant
non disponible
Personne responsable
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