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Formulation and Evaluation of Gastroretentive Drug Delivery System: A promising approach for improving bioavailability - Couverture souple

Raut, Indrayani; Chougule, D.D.; Bandgar, S.A.

 
9783843388320: Formulation and Evaluation of Gastroretentive Drug Delivery System: A promising approach for improving bioavailability
Couverture souple
ISBN 10 : 3843388326 ISBN 13 : 9783843388320
Editeur : LAP LAMBERT Academic Publishing, 2011

Synopsis

Certain drugs having poor solubility, degradation in the alkaline pH, absorbed from the proximal part of Gastrointestinal Tract and causes irritation in the stomach. Due to this reason, drug should not achieve 100% bioavailability. To overcome these, Gastroretentive drug delivery system is a promising approach for achieving prolonged and predictable drug delivery profile. Floating drug delivery is an attempt which has been made to retained the drug in the stomach as a way of increasing retention time. Such type of novel drug delivery reduces the dosing frequency which is patient compliant and delivers active entity directly to the site of action. This book therefore provides formulation method for sustained release floating tablet by using hydrophilic and hydrophobic polymers by applying factorial design and this formulations are characterized by different In vitro evaluation tests and performed In vivo evaluation on human volunteers by X-Ray studies.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Biographie de l'auteur

Indrayani D. Raut , M. Pharm (Pharmaceutics): Studied at Shivaji University, Kolhapur. Asst Professor at Rajaramabpu College of Pharmacy, Kasegaon, MS, India. Two years of teaching experience. Published 2 research papers in reputed National Journals. Research interest includes Formulation Development and Novel Drug Delivery System.

Indrayani D. Raut , M. Pharm (Pharmaceutics): Studied at Shivaji University, Kolhapur. Asst Professor at Rajaramabpu College of Pharmacy, Kasegaon, MS, India. Two years of teaching experience. Published 2 research papers in reputed National Journals. Research interest includes Formulation Development and Novel Drug Delivery System.

Indrayani D. Raut , M. Pharm (Pharmaceutics): Studied at Shivaji University, Kolhapur. Asst Professor at Rajaramabpu College of Pharmacy, Kasegaon, MS, India. Two years of teaching experience. Published 2 research papers in reputed National Journals. Research interest includes Formulation Development and Novel Drug Delivery System.

Présentation de l'éditeur

Certain drugs having poor solubility, degradation in the alkaline pH, absorbed from the proximal part of Gastrointestinal Tract and causes irritation in the stomach. Due to this reason, drug should not achieve 100% bioavailability. To overcome these, Gastroretentive drug delivery system is a promising approach for achieving prolonged and predictable drug delivery profile. Floating drug delivery is an attempt which has been made to retained the drug in the stomach as a way of increasing retention time. Such type of novel drug delivery reduces the dosing frequency which is patient compliant and delivers active entity directly to the site of action. This book therefore provides formulation method for sustained release floating tablet by using hydrophilic and hydrophobic polymers by applying factorial design and this formulations are characterized by different In vitro evaluation tests and performed In vivo evaluation on human volunteers by X-Ray studies.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2011
Langue
anglais
ISBN 10 
3843388326
ISBN 13 
9783843388320
Reliure
Broché
Nombre de pages
136
Coordonnées du fabricant
non disponible
Personne responsable
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