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Intestinal Permeability Studies: Techniques for prediction and their application in biopharmaceutical classification of compounds - Couverture souple

Zakeri-Milani, Parvin; Valizadeh, Hadi; Tajerzadeh, H.

 
9783843392273: Intestinal Permeability Studies: Techniques for prediction and their application in biopharmaceutical classification of compounds
Couverture souple
ISBN 10 : 3843392277 ISBN 13 : 9783843392273
Editeur : LAP LAMBERT Academic Publishing, 2011

Synopsis

Over the recent years, interest has grown in using in-vitro and in-situ methods to predict as early as possible in-vivo oral absorption potential of a drug, to determine the mechanism and rate of transport across the intestinal mucosa and to alert the possible windows of absorption and also possible restrictions to the formulation approach. Since human in-vivo studies are not feasible, this prediction is of considerable interest at an early stage of drug development. This book is meant to provide an overview on various in-vitro and in-situ models for the study of drug transport, with an emphasis on in-situ perfusion and cell culture techniques, and data generated for each model for drugs with a broad range of physicochemical properties.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

Over the recent years, interest has grown in using in-vitro and in-situ methods to predict as early as possible in-vivo oral absorption potential of a drug, to determine the mechanism and rate of transport across the intestinal mucosa and to alert the possible windows of absorption and also possible restrictions to the formulation approach. Since human in-vivo studies are not feasible, this prediction is of considerable interest at an early stage of drug development. This book is meant to provide an overview on various in-vitro and in-situ models for the study of drug transport, with an emphasis on in-situ perfusion and cell culture techniques, and data generated for each model for drugs with a broad range of physicochemical properties.

Biographie de l'auteur

Parvin Zakeri-Milani: PharmD, PhD, Faculty of Pharmacy and Drug Applied Research Center, Tabriz University of Medical Sciences, Hadi Valizadeh: PharmD, PhD, Faculty of Pharmacy and Pharmaceutical Nanotechnology Research Center,Tabriz University of Medical Sciences. Hosnieh Tajerzadeh: PharmD, PhD, Tehran University of Medical Sciences.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2011
Langue
anglais
ISBN 10 
3843392277
ISBN 13 
9783843392273
Reliure
Broché
Nombre de pages
180
Coordonnées du fabricant
non disponible
Personne responsable
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