A New Algorithm for the Management of Dermatofibrosarcoma Protuberans - Couverture souple

Goldberg, Carolyn; Narayan, Deepak

 
9783843392365: A New Algorithm for the Management of Dermatofibrosarcoma Protuberans
Couverture souple
ISBN 10 : 3843392366 ISBN 13 : 9783843392365
Editeur : LAP LAMBERT Academic Publishing, 2011

Synopsis

The purpose of this project was to design an algorithm for the management of Dermatofibrosarcom Protuberans (DFSP.) The National Cancer Center Network guidelines suggest immediate reconstruction in most cases after DFSP resection. We believe this algorithm is inadequate. Due to the infiltrating nature of DFSP, tumor margins are often positive after resection. Immediate reconstruction in the context of residual tumor is problematic because of the risk for spreading microscopic disease and the potential to compromise reconstructive options. Here we examined the prevalence of positive margins on permanent pathology after immediate closure following surgical resection of DFSP. Forty percent of patients who underwent immediate closure were found to have positive margins on permanent pathology. Given these findings, we propose a treatment algorithm focused on more conservative surgical management of DFSP in which negative margins are established before closure. Mohs surgery, which allows for immediate identification of pathology, plays a central role.

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Présentation de l'éditeur

The purpose of this project was to design an algorithm for the management of Dermatofibrosarcom Protuberans (DFSP.) The National Cancer Center Network guidelines suggest immediate reconstruction in most cases after DFSP resection. We believe this algorithm is inadequate. Due to the infiltrating nature of DFSP, tumor margins are often positive after resection. Immediate reconstruction in the context of residual tumor is problematic because of the risk for spreading microscopic disease and the potential to compromise reconstructive options. Here we examined the prevalence of positive margins on permanent pathology after immediate closure following surgical resection of DFSP. Forty percent of patients who underwent immediate closure were found to have positive margins on permanent pathology. Given these findings, we propose a treatment algorithm focused on more conservative surgical management of DFSP in which negative margins are established before closure. Mohs surgery, which allows for immediate identification of pathology, plays a central role.

Biographie de l'auteur

Carolyn Goldberg graduated from Brown University in 2005 and from Yale School of Medicine in 2010. She is currently a resident in Plastic and Reconstructive Surgery at the University of Wisconsin.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2011
Langue
anglais
ISBN 10 
3843392366
ISBN 13 
9783843392365
Reliure
Broché
Nombre de pages
52
Coordonnées du fabricant
non disponible
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