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Présentation de l'éditeur :
Stroke is the second leading cause of death in the world. Ischemic stroke is characterized by rapid onset of neurological injury due to interruption of blood flow to the brain. Free radicals have been implicated in cerebral ischemia and reperfusion- induced neuronal injury. Hence anti-oxidants have shown neuroprotective effect.The present study investigates the effect of methanolic extracts of a natural anti-oxidant plant - Allium cepa on ischemia and reperfusion induced cerebral injury. Global cerebral ischemia was induced by bilateral carotid artery occlusion for 10 min followed by reperfusion for 24 hr. Cerebral infarct size was estimated using triphenyltetrazolium chloride staining. TBARS assay was employed to measure oxidative stress. Elevated plus maze was employed to evaluate short-term memory. Motor incoordination was evaluated using inclined-beam walking test.Pretreatment with onion extracts reduced cerebral infarct size, attenuated impairment in short term memory and motor coordination along with a decrease in mitochondrial TBARS. Hence, antioxidant plant extracts that attenuate cerebral injury may play an important role in neuroprotection.
Biographie de l'auteur :
Dr Richa Shri teaches at the Department of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, India. She studied from UIPS,Chandigarh. Her special areas of interest are evaluation of plants with neuroprotective effect and antianxiety activity and validation of traditional remedies. Mr KS Bora teaches at LR college, Solan.
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- ÉditeurLAP LAMBERT Academic Publishing
- Date d'édition2011
- ISBN 10 3844302360
- ISBN 13 9783844302363
- ReliureBroché
- Nombre de pages100
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The Role of Onion Extracts in the Prevention of Stroke
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The Role of Onion Extracts in The Prevention of Stroke: Neuroprotective effect of onion extracts
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Description du livre Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Stroke is the second leading cause of death in the world. Ischemic stroke is characterized by rapid onset of neurological injury due to interruption of blood flow to the brain. Free radicals have been implicated in cerebral ischemia and reperfusion- induced neuronal injury. Hence anti-oxidants have shown neuroprotective effect.The present study investigates the effect of methanolic extracts of a natural anti-oxidant plant - Allium cepa on ischemia and reperfusion induced cerebral injury. Global cerebral ischemia was induced by bilateral carotid artery occlusion for 10 min followed by reperfusion for 24 hr. Cerebral infarct size was estimated using triphenyltetrazolium chloride staining. TBARS assay was employed to measure oxidative stress. Elevated plus maze was employed to evaluate short-term memory. Motor incoordination was evaluated using inclined-beam walking test.Pretreatment with onion extracts reduced cerebral infarct size, attenuated impairment in short term memory and motor coordination along with a decrease in mitochondrial TBARS. Hence, antioxidant plant extracts that attenuate cerebral injury may play an important role in neuroprotection. 100 pp. Englisch. N° de réf. du vendeur 9783844302363
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The Role of Onion Extracts in The Prevention of Stroke Neuroprotective effect of onion extracts
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The Role of Onion Extracts in The Prevention of Stroke : Neuroprotective effect of onion extracts
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Description du livre Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Stroke is the second leading cause of death in the world. Ischemic stroke is characterized by rapid onset of neurological injury due to interruption of blood flow to the brain. Free radicals have been implicated in cerebral ischemia and reperfusion- induced neuronal injury. Hence anti-oxidants have shown neuroprotective effect.The present study investigates the effect of methanolic extracts of a natural anti-oxidant plant - Allium cepa on ischemia and reperfusion induced cerebral injury. Global cerebral ischemia was induced by bilateral carotid artery occlusion for 10 min followed by reperfusion for 24 hr. Cerebral infarct size was estimated using triphenyltetrazolium chloride staining. TBARS assay was employed to measure oxidative stress. Elevated plus maze was employed to evaluate short-term memory. Motor incoordination was evaluated using inclined-beam walking test.Pretreatment with onion extracts reduced cerebral infarct size, attenuated impairment in short term memory and motor coordination along with a decrease in mitochondrial TBARS. Hence, antioxidant plant extracts that attenuate cerebral injury may play an important role in neuroprotection. N° de réf. du vendeur 9783844302363
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The Role of Onion Extracts in The Prevention of Stroke Neuroprotective effect of onion extracts
Edité par
LAP LAMBERT Academic Publishing
(2011)
ISBN 10 : 3844302360
ISBN 13 : 9783844302363
Neuf
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Description du livre PAP. Etat : New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000. N° de réf. du vendeur L0-9783844302363
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The Role of Onion Extracts in The Prevention of Stroke
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Description du livre Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Shri RichaDr Richa Shri teaches at the Department of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, India. She studied from UIPS,Chandigarh. Her special areas of interest are evaluation of plants with ne. N° de réf. du vendeur 5470741
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