Articles liés à Malaria Vaccine Development: A Recombinant BCG-Based...
Malaria Vaccine Development: A Recombinant BCG-Based Vaccine Expressing Blood-Stage Antigen of P. Falciparum - Couverture souple
Synopsis
Vaccine development against blood-stage antigens is aimed at inducing inhibitory antibodies towards the circulating merozoites, thus preventing them from infecting red blood cells. One such blood stage candidate is the 19 kDa C-terminus of merozoite surface protein-1 (MSP-1C). MSP-1C has been shown to induce both inhibitory as well as blocking antibodies, the latter blocking the protective effects of the former. Inhibitory antibodies will bind to MSP-1C and inhibit merozoite invasion of red blood cell but the binding of blocking antibodies can prevent binding of inhibitory antibodies thereby allowing the parasite to invade an erythrocyte. This book provides some information regarding the development of blood-stage malaria vaccine based on mutated version of MSP-1C which induces inhibitory antibodies against malarial parasite. The use of live recombinant Mycobacterium bovis bacille Calmette Guerin as a vaccine vehicle was also described in this book. The rBCG expressing the mutated version of MSP-1C was found to induce some level of protections against P. falciparum; thus paving the way for the rational use of rBCG as a blood-stage malaria vaccine candidate.
Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.
Présentation de l'éditeur
Vaccine development against blood-stage antigens is aimed at inducing inhibitory antibodies towards the circulating merozoites, thus preventing them from infecting red blood cells. One such blood stage candidate is the 19 kDa C-terminus of merozoite surface protein-1 (MSP-1C). MSP-1C has been shown to induce both inhibitory as well as blocking antibodies, the latter blocking the protective effects of the former. Inhibitory antibodies will bind to MSP-1C and inhibit merozoite invasion of red blood cell but the binding of blocking antibodies can prevent binding of inhibitory antibodies thereby allowing the parasite to invade an erythrocyte. This book provides some information regarding the development of blood-stage malaria vaccine based on mutated version of MSP-1C which induces inhibitory antibodies against malarial parasite. The use of live recombinant Mycobacterium bovis bacille Calmette Guerin as a vaccine vehicle was also described in this book. The rBCG expressing the mutated version of MSP-1C was found to induce some level of protections against P. falciparum; thus paving the way for the rational use of rBCG as a blood-stage malaria vaccine candidate.
Biographie de l'auteur
Nurul Asma Abdullah, BSc (HON), PhD; Lecturer of Microbiology and Immunology at Universiti Sains Malaysia, Malaysia. Norazmi Mohd Nor, BSc (HON), PhD; Professor in Molecular Immunology at Universiti Sains Malaysia.
Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.
Acheter neuf
Afficher cet article
EUR 55,21
EUR 9,70 expédition depuis Allemagne vers France
Destinations, frais et délaisRésultats de recherche pour Malaria Vaccine Development: A Recombinant BCG-Based...
Image fournie par le vendeur
Malaria Vaccine Development
Edité par
LAP LAMBERT Academic Publishing, 2011
ISBN 10 : 384430486X
ISBN 13 : 9783844304862
Neuf
Couverture souple
Vendeur : moluna, Greven, Allemagne
Évaluation du vendeur 5 sur 5 étoiles
Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Abdullah Nurul AsmaNurul Asma Abdullah, BSc (HON), PhD Lecturer of Microbiology and Immunology at Universiti Sains Malaysia, Malaysia. Norazmi Mohd Nor, BSc (HON), PhD Professor in Molecular Immunology at Universiti Sains Malaysia. N° de réf. du vendeur 5470981
Quantité disponible : Plus de 20 disponibles
Image fournie par le vendeur
Malaria Vaccine Development : A Recombinant BCG-Based Vaccine Expressing Blood-Stage Antigen of P. Falciparum
Edité par
LAP LAMBERT Academic Publishing, 2011
ISBN 10 : 384430486X
ISBN 13 : 9783844304862
Neuf
Taschenbuch
Vendeur : AHA-BUCH GmbH, Einbeck, Allemagne
Évaluation du vendeur 5 sur 5 étoiles
Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Vaccine development against blood-stage antigens is aimed at inducing inhibitory antibodies towards the circulating merozoites, thus preventing them from infecting red blood cells. One such blood stage candidate is the 19 kDa C-terminus of merozoite surface protein-1 (MSP-1C). MSP-1C has been shown to induce both inhibitory as well as blocking antibodies, the latter blocking the protective effects of the former. Inhibitory antibodies will bind to MSP-1C and inhibit merozoite invasion of red blood cell but the binding of blocking antibodies can prevent binding of inhibitory antibodies thereby allowing the parasite to invade an erythrocyte. This book provides some information regarding the development of blood-stage malaria vaccine based on mutated version of MSP-1C which induces inhibitory antibodies against malarial parasite. The use of live recombinant Mycobacterium bovis bacille Calmette Guerin as a vaccine vehicle was also described in this book. The rBCG expressing the mutated version of MSP-1C was found to induce some level of protections against P. falciparum; thus paving the way for the rational use of rBCG as a blood-stage malaria vaccine candidate. N° de réf. du vendeur 9783844304862
Quantité disponible : 1 disponible(s)
Image fournie par le vendeur
Malaria Vaccine Development
Edité par
LAP LAMBERT Academic Publishing Feb 2011, 2011
ISBN 10 : 384430486X
ISBN 13 : 9783844304862
Neuf
Taschenbuch
Vendeur : BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Allemagne
Évaluation du vendeur 5 sur 5 étoiles
Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Vaccine development against blood-stage antigens is aimed at inducing inhibitory antibodies towards the circulating merozoites, thus preventing them from infecting red blood cells. One such blood stage candidate is the 19 kDa C-terminus of merozoite surface protein-1 (MSP-1C). MSP-1C has been shown to induce both inhibitory as well as blocking antibodies, the latter blocking the protective effects of the former. Inhibitory antibodies will bind to MSP-1C and inhibit merozoite invasion of red blood cell but the binding of blocking antibodies can prevent binding of inhibitory antibodies thereby allowing the parasite to invade an erythrocyte. This book provides some information regarding the development of blood-stage malaria vaccine based on mutated version of MSP-1C which induces inhibitory antibodies against malarial parasite. The use of live recombinant Mycobacterium bovis bacille Calmette Guerin as a vaccine vehicle was also described in this book. The rBCG expressing the mutated version of MSP-1C was found to induce some level of protections against P. falciparum; thus paving the way for the rational use of rBCG as a blood-stage malaria vaccine candidate. 180 pp. Englisch. N° de réf. du vendeur 9783844304862
Quantité disponible : 2 disponible(s)
Image fournie par le vendeur
Malaria Vaccine Development
Edité par
LAP LAMBERT Academic Publishing Feb 2011, 2011
ISBN 10 : 384430486X
ISBN 13 : 9783844304862
Neuf
Taschenbuch
Vendeur : buchversandmimpf2000, Emtmannsberg, BAYE, Allemagne
Évaluation du vendeur 5 sur 5 étoiles
Taschenbuch. Etat : Neu. Neuware -Vaccine development against blood-stage antigens is aimed at inducing inhibitory antibodies towards the circulating merozoites, thus preventing them from infecting red blood cells. One such blood stage candidate is the 19 kDa C-terminus of merozoite surface protein-1 (MSP-1C). MSP-1C has been shown to induce both inhibitory as well as blocking antibodies, the latter blocking the protective effects of the former. Inhibitory antibodies will bind to MSP-1C and inhibit merozoite invasion of red blood cell but the binding of blocking antibodies can prevent binding of inhibitory antibodies thereby allowing the parasite to invade an erythrocyte. This book provides some information regarding the development of blood-stage malaria vaccine based on mutated version of MSP-1C which induces inhibitory antibodies against malarial parasite. The use of live recombinant Mycobacterium bovis bacille Calmette Guerin as a vaccine vehicle was also described in this book. The rBCG expressing the mutated version of MSP-1C was found to induce some level of protections against P. falciparum; thus paving the way for the rational use of rBCG as a blood-stage malaria vaccine candidate.Books on Demand GmbH, Überseering 33, 22297 Hamburg 180 pp. Englisch. N° de réf. du vendeur 9783844304862
Quantité disponible : 2 disponible(s)