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Performing Enzymatic Reactions Using Novel Polymer-Bound ATP: Enzymatic Production of Glucose 6-Phosphate Using Novel Polymer-bound ATP in Membrane Reactors - Couverture souple

Abdelmoez, Wael

 
9783844309805: Performing Enzymatic Reactions Using Novel Polymer-Bound ATP: Enzymatic Production of Glucose 6-Phosphate Using Novel Polymer-bound ATP in Membrane Reactors

Synopsis

the present work was devoted to develop an efficient synthetic process which requires cofactors. The enzymatic glucose 6-phosphate (G6P) production from glucose was demonstrated as a model process. As cofactors, two new polymer-bound adenine nucleotides (ATP and ADP) were synthesized using starburst polyamidoamine (PAMAM) dendrimers. Then, the kinetics of the reactions catalyzed by Bacillus stearothermophilus glucokinase (GK) and acetate kinase (AK) using these polymer-bound cofactors were studied extensively. Finally, the production of G6P using the polymer-bound ATP in a plug flow-type hollow-fiber membrane reactor (PFMR) in a diffusion mode as well as a continuous stirred tank-type membrane reactor (CSTMR) in a filtration mode was investigated theoretically

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Présentation de l'éditeur

the present work was devoted to develop an efficient synthetic process which requires cofactors. The enzymatic glucose 6-phosphate (G6P) production from glucose was demonstrated as a model process. As cofactors, two new polymer-bound adenine nucleotides (ATP and ADP) were synthesized using starburst polyamidoamine (PAMAM) dendrimers. Then, the kinetics of the reactions catalyzed by Bacillus stearothermophilus glucokinase (GK) and acetate kinase (AK) using these polymer-bound cofactors were studied extensively. Finally, the production of G6P using the polymer-bound ATP in a plug flow-type hollow-fiber membrane reactor (PFMR) in a diffusion mode as well as a continuous stirred tank-type membrane reactor (CSTMR) in a filtration mode was investigated theoretically

Biographie de l'auteur

Associate Professor at Chemical Engineering Deprtment, Minia University, Egypt. Dr. Abdelmoez mixed between the academia and the professional life through being an industrial consultant for many factories. In 2003, he obtained his PhD from Japan at Osaka Prefecture University then, he worked there for another 5 years at the COE project.

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