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Studies on the immunomodulatory activity of Trapa bispinosa: Investigation in to the immunomodulatory activity of Trapa bispinosa in immunodeficient experimental animals - Couverture souple

Patel, Dr. Samir C.; M. M. Patel, Dr.; K. K. Shah, Dr.

 
9783844310313: Studies on the immunomodulatory activity of Trapa bispinosa: Investigation in to the immunomodulatory activity of Trapa bispinosa in immunodeficient experimental animals
Couverture souple
ISBN 10 : 3844310312 ISBN 13 : 9783844310313
Editeur : LAP LAMBERT Academic Publishing, 2011

Synopsis

Immunomodulation using medicinal plants can provide an alternative to conventional chemotherapy for a variety of diseases especially when host defense mechanism has to be acquired under the conditions of impaired immune responsiveness. The objective of the present study was to investigate the immunomodulatory potential of aqueous extract of Trapa bispinosa (TBAE) in immunodeficient experimental animals by studying humoral immunity response, delayed type hypersensitivity reaction, macrophase phagocytosis and percent change in neutrophil counts. Further to evaluate antistress activity, wistar rats were subjected to forced swimming endurance test and chronic cold restraint stress. The result of present study suggests that ethanolic fraction of TBAE could stimulate the cellular and humoral response in animals. The anti-stress and adaptogenic activity exhibited by its ethanol fraction in the study further suggests that its ethanolic fraction may useful in the treatment of several disorders caused by stress by its immunostimulating and immunomodulating properties and also enhancing the homeostasis mechanism.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

Immunomodulation using medicinal plants can provide an alternative to conventional chemotherapy for a variety of diseases especially when host defense mechanism has to be acquired under the conditions of impaired immune responsiveness. The objective of the present study was to investigate the immunomodulatory potential of aqueous extract of Trapa bispinosa (TBAE) in immunodeficient experimental animals by studying humoral immunity response, delayed type hypersensitivity reaction, macrophase phagocytosis and percent change in neutrophil counts. Further to evaluate antistress activity, wistar rats were subjected to forced swimming endurance test and chronic cold restraint stress. The result of present study suggests that ethanolic fraction of TBAE could stimulate the cellular and humoral response in animals. The anti-stress and adaptogenic activity exhibited by its ethanol fraction in the study further suggests that its ethanolic fraction may useful in the treatment of several disorders caused by stress by its immunostimulating and immunomodulating properties and also enhancing the homeostasis mechanism.

Biographie de l'auteur

Dr. Samir C. Patel, M.Pharm., Ph.D. Assistant Professor, Department of Pharmacology, Kalol Institute of Pharmacy, Kalol-382721, Gujarat, India.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2011
Langue
anglais
ISBN 10 
3844310312
ISBN 13 
9783844310313
Reliure
Broché
Nombre de pages
224
Coordonnées du fabricant
non disponible
Personne responsable
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