Articles liés à Cell-Based Therapy For Chronic Neuropathic Pain After...

Cell-Based Therapy For Chronic Neuropathic Pain After CNS Injury: A Neurophysiological Outlook - Couverture souple

Hains, Bryan

 
9783844326970: Cell-Based Therapy For Chronic Neuropathic Pain After CNS Injury: A Neurophysiological Outlook
Couverture souple
ISBN 10 : 3844326979 ISBN 13 : 9783844326970
Editeur : LAP LAMBERT Academic Publishing, 2011

Synopsis

Hemisection spinal cord injury (SCI) in preclinical models results in pathological and functional features that mimic the human condition. Chronic pain secondary to neuronal injury is actively and continuously modulated at multiple locations along the sensory neuraxis. Here, we describe how pain-processing neurons of the spinal cord process and communicate nociceptive information in terms of precisely calibrated firing patterns. We then discuss how several cell types, with a focus on 5-HTergic neurons, cause system-wide interference in nociceptive processing through novel signaling schema, thus contributing to sensory network plasticity and chronic pain.

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Présentation de l'éditeur

Hemisection spinal cord injury (SCI) in preclinical models results in pathological and functional features that mimic the human condition. Chronic pain secondary to neuronal injury is actively and continuously modulated at multiple locations along the sensory neuraxis. Here, we describe how pain-processing neurons of the spinal cord process and communicate nociceptive information in terms of precisely calibrated firing patterns. We then discuss how several cell types, with a focus on 5-HTergic neurons, cause system-wide interference in nociceptive processing through novel signaling schema, thus contributing to sensory network plasticity and chronic pain.

Biographie de l'auteur

Dr. Hains is currently an Adjunct Professor at the University of California, Berkeley. Previously he was an Assistant Professor of Neurology at the Yale University School of Medicine. He completed his graduate work at the University of Texas Medical Branch, and undergraduate training at Stetson University.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2011
Langue
anglais
ISBN 10 
3844326979
ISBN 13 
9783844326970
Reliure
Broché
Nombre de pages
264
Coordonnées du fabricant
non disponible
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