Neural Tube Defects and Genetic Polymorphisms: MTR(2756 A>G and 2758 C>G) and MTHFD1 1958 G>A Polymorphisms and their association with Neural Tube Defects - Couverture souple

AL Farra, Helmi Y.

 
9783844333961: Neural Tube Defects and Genetic Polymorphisms: MTR(2756 A>G and 2758 C>G) and MTHFD1 1958 G>A Polymorphisms and their association with Neural Tube Defects
Couverture souple
ISBN 10 : 3844333967 ISBN 13 : 9783844333961
Editeur : LAP LAMBERT Academic Publishing, 2011

Synopsis

The neural tube is the embryonic precursor of the brain and the spinal cord. Building a neural tube is an extremely complex phenomenon where cells need to change in shape, migrate and differentiate to form a hollown tube from a flat sheet of thickened epithelial cells (the neural plate). The normal closure of the neural plate occurs very early in human pregnancy from day 21 until day 28 following conception or 1 weak after the expected menstruation. Abnormal closure of the neural plate results in neural tube defects (NTDs). The orrelation between the birth of NTD affected children and the maternal polymorphisms of two genes related to the folate metabolic pathway, studied methylenetetrahydrofolate-dehydrogenase (MTHFD1) 1958 (G>A) and methionine synthase polymorphisms MTR 2756 (A>G) and MTR 2758(C>G) in the Jordanian population have been examined in this original study.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

The neural tube is the embryonic precursor of the brain and the spinal cord. Building a neural tube is an extremely complex phenomenon where cells need to change in shape, migrate and differentiate to form a hollown tube from a flat sheet of thickened epithelial cells (the neural plate). The normal closure of the neural plate occurs very early in human pregnancy from day 21 until day 28 following conception or 1 weak after the expected menstruation. Abnormal closure of the neural plate results in neural tube defects (NTDs). The orrelation between the birth of NTD affected children and the maternal polymorphisms of two genes related to the folate metabolic pathway, studied methylenetetrahydrofolate-dehydrogenase (MTHFD1) 1958 (G>A) and methionine synthase polymorphisms MTR 2756 (A>G) and MTR 2758(C>G) in the Jordanian population have been examined in this original study.

Biographie de l'auteur

Master of Biotechnology and Molecular Genetics Yarmouk University of Jordan Bachelor of Biology Islamic University of Gaza palestine

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2011
Langue
anglais
ISBN 10 
3844333967
ISBN 13 
9783844333961
Reliure
Broché
Nombre de pages
116
Coordonnées du fabricant
non disponible
Personne responsable
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