Surface Modification Of Polymer Constructs For Tissue Engineering: Polymer Scaffold Modification and Characterisation for Tissue Engineering Applications - Couverture souple

Safinia, Laleh

 
9783844386721: Surface Modification Of Polymer Constructs For Tissue Engineering: Polymer Scaffold Modification and Characterisation for Tissue Engineering Applications
Couverture souple
ISBN 10 : 3844386726 ISBN 13 : 9783844386721
Editeur : LAP LAMBERT Academic Publishing, 2012

Présentation de l'éditeur

One of the major issues in tissue engineering is the seeding of mammalian cells onto natural or synthetic scaffolds, to which the cells should attach and colonise into three-dimensional (3D) orientation, defining the shape of the tissue. The structural and surface properties of the biomaterials used to make the scaffolds, such as pore structure, hydrophilicity and surface charge are therefore important parameters to consider, if they are to be used as supportive 3D matrices for cells, providing a strong mechanical contact between the cells and the scaffold. In this work, a variety of synthetic polymer scaffolds was fabricated via thermally induced phase separation (TIPS) followed by freeze-drying. The polymers under study were two biodegradable polyesters, poly (D,L-lactide) (PDLLA) and poly (lactide-co-glycolide) (PLGA) and two non-biodegradable polymers, polystyrene (PS) and polyurethane (PU). For the design and reproducible fabrication of polymer scaffolds, tailored for directed tissue growth, pore structure and surface chemistry of the selected polymer scaffolds were studied.

Biographie de l'auteur

Laleh Safinia holds the position of Business Development Manager for EMEA Emerging Markets at Janssen (J&J). She completed her BEng (Hons) in Biochemical Engineering from University College London, PhD (Honorary Distinction) and a Post Doctorate in Chemical Engineering from Imperial College and completed her MBA (Hons) from Cass Business School.

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Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2012
Langue
anglais
ISBN 10 
3844386726
ISBN 13 
9783844386721
Reliure
Broché
Nombre de pages
180
Coordonnées du fabricant
non disponible
Personne responsable
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