Articles liés à Solid Phase Synthesis of Thioredoxin Sequences: An...

Solid Phase Synthesis of Thioredoxin Sequences: An Analytical Approach - Couverture souple

T. Varkey, Jaya

 
9783845428840: Solid Phase Synthesis of Thioredoxin Sequences: An Analytical Approach
Couverture souple
ISBN 10 : 3845428848 ISBN 13 : 9783845428840
Editeur : LAP LAMBERT Academic Publishing, 2011

Synopsis

It has been nearly fifty years since the advent of solid phase method for the assembly of peptides. One of the main difficulties facing researchers in this field is that of obtaining quantities of peptides and proteins in a pure state. Isolation of proteins form natural resources can be laborious and often provides only tiny quantities. Investigations dealing with the quantitative aspects of polymer-supported reactions have shown that the insoluble support does have a significant dynamic influence on the bound substrates. An efficient polymeric support for peptdide synthesis should have optimum hydrophobic-hydrophilic balance compatible with the peptide being synthesized. This book illustrates the synthesis and characterization of a novel polymer support, polystyrene crosslinked with 1,6-hexanediol diacrylate for the successful synthesis of peptides. The compatibility of the new support is proved by synthesizing sequences of Thioredoxin, which is otherwise difficult to synthesize. Thioredoxin is a naturally occurring sulphur reducing protein containing 108 amino acids. The book is useful to researchers, scientists and academia in studying the intricacies of solid phase synthesis.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

It has been nearly fifty years since the advent of solid phase method for the assembly of peptides. One of the main difficulties facing researchers in this field is that of obtaining quantities of peptides and proteins in a pure state. Isolation of proteins form natural resources can be laborious and often provides only tiny quantities. Investigations dealing with the quantitative aspects of polymer-supported reactions have shown that the insoluble support does have a significant dynamic influence on the bound substrates. An efficient polymeric support for peptdide synthesis should have optimum hydrophobic-hydrophilic balance compatible with the peptide being synthesized. This book illustrates the synthesis and characterization of a novel polymer support, polystyrene crosslinked with 1,6-hexanediol diacrylate for the successful synthesis of peptides. The compatibility of the new support is proved by synthesizing sequences of Thioredoxin, which is otherwise difficult to synthesize. Thioredoxin is a naturally occurring sulphur reducing protein containing 108 amino acids. The book is useful to researchers, scientists and academia in studying the intricacies of solid phase synthesis.

Biographie de l'auteur

Jaya T. Varkey Ph.D:Graduated in Chemistry (Cochin University of Science and Technology, India), PhD in Chemistry (Chemical Sciences, M. G. University, Kerala, India), Post Doctoral Fellow (University of Minnesota, USA). National Young Scientist award winner (1995). Currently Assistant Professor in Chemistry, St. Teresa's College, Kerala, India.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2011
Langue
anglais
ISBN 10 
3845428848
ISBN 13 
9783845428840
Reliure
Broché
Nombre de pages
140
Coordonnées du fabricant
non disponible
Personne responsable
KreGa Onlinehandel GmbH
4950000000000
info@krega-onlinehandel.de

Birkenweg 31
Brakel
33034
Allemagne