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Study of serum metals and DNA damage: in patients with coronary artery disease(CAD) - Couverture souple

Veerabathiran, Dr.Ramakrishnan; Vincent, Dr.S.

 
9783846503928: Study of serum metals and DNA damage: in patients with coronary artery disease(CAD)
Couverture souple
ISBN 10 : 3846503924 ISBN 13 : 9783846503928
Editeur : LAP LAMBERT Academic Publishing, 2011

Synopsis

Coronary artery disease (CAD) is one of the major health problems responsible for increasing mortality and morbidity all over the world. The hypothesis of the study is that elevated levels of antioxidant enzymes are associated with increased stable coronary artery disease. With this perspective in the study, the role of trace elements, lipids and antioxidant enzymes levels in the serum of patients with CAD were determined and the presence of DNA damage in peripheral blood lymphocytes in these patients was also verified. Our findings reports that the increased DNA damages are found in CAD patients’ who have been analyzed for high or moderate risk of triple vessel disease by duke treadmill score (DTS) and coronary angiogram successively. Moreover evaluation of the association of angiotensin converting enzyme (ACE) gene with coronary artery disease (CAD) has suggested that there is no association of Deletion (D) or insertion (I) alleles with CAD. The study implies that the trace elements will have reliable prognostic value in the diagnosis of CAD if the investigation is carried out on the extent of the changes of these elements in CAD patients.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

Coronary artery disease (CAD) is one of the major health problems responsible for increasing mortality and morbidity all over the world. The hypothesis of the study is that elevated levels of antioxidant enzymes are associated with increased stable coronary artery disease. With this perspective in the study, the role of trace elements, lipids and antioxidant enzymes levels in the serum of patients with CAD were determined and the presence of DNA damage in peripheral blood lymphocytes in these patients was also verified. Our findings reports that the increased DNA damages are found in CAD patients’ who have been analyzed for high or moderate risk of triple vessel disease by duke treadmill score (DTS) and coronary angiogram successively. Moreover evaluation of the association of angiotensin converting enzyme (ACE) gene with coronary artery disease (CAD) has suggested that there is no association of Deletion (D) or insertion (I) alleles with CAD. The study implies that the trace elements will have reliable prognostic value in the diagnosis of CAD if the investigation is carried out on the extent of the changes of these elements in CAD patients.

Biographie de l'auteur

Dr.V.RAMAKRISHNAN and Dr.VINCENTThis monograph from the doctoral thesis work from the author Dr.V.Ramakrishnan.This work has been carried out in the Department of Advanced Zoology and Biotechnology and obtained the PhD degree in 2009 from University of Madras.Currently he is a faculty in Chettinad University,Kelambakkam,Chennai-601 103.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2011
Langue
anglais
ISBN 10 
3846503924
ISBN 13 
9783846503928
Reliure
Broché
Nombre de pages
224
Coordonnées du fabricant
non disponible
Personne responsable
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