Simvastatin Solid Dispersion Prepared By Microwave Fusion Technique - Couverture souple

Chaudhary, Haresh; Patel, B.N.; Patel, D.M.

 
9783846504055: Simvastatin Solid Dispersion Prepared By Microwave Fusion Technique
Couverture souple
ISBN 10 : 384650405X ISBN 13 : 9783846504055
Editeur : LAP LAMBERT Academic Publishing, 2014

Synopsis

Simvastatin, a crystalline substance, is a widely used drug for the treatment of hypercholesterolemia. It is a BCS class II drug, having low aqueous solubility (0.76 mg/L) exhibiting poor dissolution pattern and low oral bioavailability (5%). The purpose of this study was to apply the attractive technique of the microwaves fusion for the preparation of solvent-Simvastatin, a crystalline substance, is a widely used drug for the treatment of hypercholesterolemia. It is a BCS class II drug, having low aqueous solubility (0.76 mg/L) exhibiting poor dissolution pattern and low oral bioavailability (5%). The purpose of this study was to apply the attractive technique of the microwaves fusion for the preparation of solvent-free solid dispersions and to enhance the solubility and dissolution rate of simvastatin by a solid dispersion.

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À propos de l?auteur

Haresh Chaudhary has completed B.pharm and M.pharm from Shri Sarvajanik Pharmacy College,Mehsana and currently working in Formulation Development Department at Cadila Healthcare Ltd, Ahmedabad. He is energetic person with positive attitude toward his goal.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2014
Langue
anglais
ISBN 10 
384650405X
ISBN 13 
9783846504055
Reliure
Broché
Nombre de pages
124
Coordonnées du fabricant
non disponible
Personne responsable
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