Articles liés à Hepatoprotective activity of caesalpinia bonduc: caesalpinia...

Hepatoprotective activity of caesalpinia bonduc: caesalpinia bonduc- Hepatoprotective plant - Couverture souple

Mandade, Rajesh

 
9783846515754: Hepatoprotective activity of caesalpinia bonduc: caesalpinia bonduc- Hepatoprotective plant
Couverture souple
ISBN 10 : 3846515752 ISBN 13 : 9783846515754
Editeur : LAP LAMBERT Academic Publishing, 2011

Synopsis

Liver is the most important organ, which plays a pivotal role in regulating various physiological processes in the body. It is involved in several vital functions, such as metabolism, secretion and storage. Therefore, damage to liver inflicted by hepatotoxic agents is of grave concern. Modern medicine offered little protection with maximum side effects. Nearly 150 phytoconstituents from 101 plants have been claimed to possess liver protecting activity. At the same time, surprisingly, we do not have readily available satisfactory plant drugs/formulations to treat severe liver disease. The present study was carried out to evaluate the hepatoprotective of ethanolic extract of Caesalpinia bonduc using various animal screening models. CCl4 and Paracetamol challenged animal’s demonstrated significant rise in the level of liver weight, liver volume, serum marker enzymes like AST, ALT, ALP and total and direct bilirubin. Ethanolic extract of C. bonduc brought down levels of all serum marker enzymes to normal and effects found to be comparable with that of standard drug silymarin. From results it can be concluded that ethanolic extract of C. bonduc possess hepatoprotective activity.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

Liver is the most important organ, which plays a pivotal role in regulating various physiological processes in the body. It is involved in several vital functions, such as metabolism, secretion and storage. Therefore, damage to liver inflicted by hepatotoxic agents is of grave concern. Modern medicine offered little protection with maximum side effects. Nearly 150 phytoconstituents from 101 plants have been claimed to possess liver protecting activity. At the same time, surprisingly, we do not have readily available satisfactory plant drugs/formulations to treat severe liver disease. The present study was carried out to evaluate the hepatoprotective of ethanolic extract of Caesalpinia bonduc using various animal screening models. CCl4 and Paracetamol challenged animal’s demonstrated significant rise in the level of liver weight, liver volume, serum marker enzymes like AST, ALT, ALP and total and direct bilirubin. Ethanolic extract of C. bonduc brought down levels of all serum marker enzymes to normal and effects found to be comparable with that of standard drug silymarin. From results it can be concluded that ethanolic extract of C. bonduc possess hepatoprotective activity.

Biographie de l'auteur

Rajesh Mandade has obtained his M.Pharm degree in Pharmacology from SRM University, Chennai in the year 2007. At present he is working as Assistant professor at Sudhakarrao Naik Institute of Pharmacy, Pusad. He has worked in different projects in the field of Pharmacology. He is the author of several articles published in reputed journals.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2011
Langue
anglais
ISBN 10 
3846515752
ISBN 13 
9783846515754
Reliure
Broché
Nombre de pages
104
Coordonnées du fabricant
non disponible
Personne responsable
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